Results 11 to 20 of about 87,711 (206)
The Structure of Glycosaminoglycans and their Interactions with Proteins
Chemical Biology and Drug Design, 2008 Neha S Gandhi, Ricardo L Mancera
exaly +2 more sources
Glycosaminoglycans: What Remains To Be Deciphered?
JACS Au, 2023 Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural diversity and fulfilling various functions mediated by thousands of interactions in the extracellular matrix, at the cell surface, and within the cells where they have ...
S. Pérez +18 more
semanticscholar +1 more source
Biomolecules, 2021 We analyzed children with urolithiasis with age- and gender-matched healthy children. Calcium (mmol/mmol creatinine) and the calcium/citrate ratio (mol/mmol) are the only variables that differentiate children before puberty from healthy children (ROC ...
Daniel Turudic +4 more
doaj +1 more source
Click-Chemistry-Assisted Alteration of Glycosaminoglycans for Biological Applications
SynOpen, 2023 This short review describes the assistance of click chemistry in the chemical modification of glycosaminoglycans. Through an alkyne-azide 1,3-dipolar cycloaddition reaction, the chemically and physiologically stable triazole unit connects ...
Smritilekha Bera, Dhananjoy Mondal
doaj +1 more source
Roles of Proteoglycans and Glycosaminoglycans in Cancer Development and Progression
International Journal of Molecular Sciences, 2020 The extracellular matrix (ECM) spatiotemporally controls cell fate; however, dysregulation of ECM remodeling can lead to tumorigenesis and cancer development by providing favorable conditions for tumor cells.
Jinfen Wei +4 more
semanticscholar +1 more source
High sensitivity analysis of nanogram quantities of glycosaminoglycans using ToF-SIMS
Communications Chemistry, 2021 Glycosaminoglycans are an important class of carbohydrates, but pose substantial analytical challenges. Here ToF-SIMS combined with multivariate analysis distinguishes six classes of glycosaminoglycans, including distinguishing heparin samples from ...
Andrew L. Hook +4 more
doaj +1 more source
Vascular Dysfunction in Malaria: Understanding the Role of the Endothelial Glycocalyx
Frontiers in Cell and Developmental Biology, 2021 Malaria caused by Plasmodium falciparum results in over 400,000 deaths annually, predominantly affecting African children. In addition, non-falciparum species including vivax and knowlesi cause significant morbidity and mortality. Vascular dysfunction is
Margaret A. Bush +8 more
doaj +1 more source
Nature Communications, 2020 The human gut microbiota (HGM), which is critical to human health, utilises complex glycans as its major carbon source. Glycosaminoglycans represent an important, high priority, nutrient source for the HGM.
D. Ndeh +7 more
semanticscholar +1 more source
Mathematical Modeling of Microscale Biology: Ion Pairing, Dielectric Decrement, and Born Energy in Glycosaminoglycan Brushes [PDF]
, 2022 Biological macromolecules including nucleic acids, proteins, and glycosaminoglycans are typically anionic and can span domains of up to hundreds of nanometers and even micron length scales. The structures exist in crowded environments that are dominated by weak multivalent electrostatic interactions that can be modeled using mean field continuum ...
arxiv +1 more source
Frontiers in Microbiology, 2023 Enterococcus faecalis is a commensal bacterium of the gastrointestinal tract but also a major nosocomial pathogen. This bacterium uses regulators like BglG/SacY family of transcriptional antiterminators to adapt its metabolism during host colonization ...
Diane Soussan +18 more
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