Results 21 to 30 of about 88,369 (330)

Human milk glycosaminoglycans: the state of the art and future perspectives

Italian Journal of Pediatrics, 2013
Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern ...
Coppa Giovanni Valentino, Gabrielli Orazio, Bertino Enrico, Zampini Lucia, Galeazzi Tiziana, Padella Lucia, Santoro Lucia, Marchesiello Rita Lucia, Galeotti Fabio, Maccari Francesca, Volpi Nicola   +10 more
doaj   +1 more source

FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder

EMBO Molecular Medicine, 2022
Whole‐exome sequencing of two patients with idiopathic complex neurodevelopmental disorder (NDD) identified biallelic variants of unknown significance within FIBCD1, encoding an endocytic acetyl group‐binding transmembrane receptor with no known function
Christopher W Fell, Astrid Hagelkruys, Ana Cicvaric, Marion Horrer, Lucy Liu, Joshua Shing Shun Li, Johannes Stadlmann, Anton A Polyansky, Stefan Mereiter, Miguel Angel Tejada, Tomislav Kokotović, Venkat Swaroop Achuta, Angelica Scaramuzza, Kimberly A Twyman, Michelle M Morrow, Jane Juusola, Huifang Yan, Jingmin Wang, Margit Burmeister, Biswa Choudhury, Thomas Levin Andersen, Gerald Wirnsberger, Uffe Holmskov, Norbert Perrimon, Bojan Žagrović, Francisco J Monje, Jesper Bonnet Moeller, Josef M Penninger, Vanja Nagy   +28 more
doaj   +1 more source

Melittin-Related Peptides Interfere with Sandfly Fever Naples Virus Infection by Interacting with Heparan Sulphate

Microorganisms, 2023
Emerging viruses pose an important global public health challenge, and early action is needed to control their spread. The Bunyaviridae family contains a great number of arboviruses which are potentially pathogenic for humans.
Annalisa Chianese, Carla Zannella, Francesca Palma, Laura Di Clemente, Alessandra Monti, Nunzianna Doti, Anna De Filippis, Massimiliano Galdiero   +7 more
doaj   +1 more source

HIGH LEVEL OF GLYCOSAMINOGLYCANS OF BLOOD SERUM AS AN INDEPENDENT PREDICTOR OF THE DEVELOPING PERITONEUM ADHESIVE DISEASE

Креативная хирургия и онкология, 2017
Peritoneal commissures is the phenomenon of adhesions formation with apparent symptom group of violations in functioning of the gastrointestinal tract and small pelvis.
I. F. Sufiyarov, A. G. Khasanov, M. A. Nurtdinov, A. V. Samorodov, G. R. Jamalova   +4 more
doaj   +1 more source

Operation spinal cord regeneration: Patterning information residing in extracellular matrix glycosaminoglycans

Brain and Behavior, 2020
Introduction Spinal cord injuries are devastating, with many complications beyond paralysis and loss of sensory function. Although spinal cord regeneration can revolutionize treatment for spinal cord injuries, the goal has not yet been achieved.
Alexander Lu, Alaina Baker‐Nigh, Peng Sun   +2 more
doaj   +1 more source

Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle

Clinics, 2010
OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI ...
Jairo Jose Matozinho Cubas, Ricardo Santos Simões, Ricardo Martins Oliveira-Filho, Manuel Jesus Simões, Edmund C Baracat, José Maria Soares-Jr   +5 more
doaj   +1 more source

Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing

Advanced Science, 2021
Excessive inflammation often impedes the healing of chronic wounds. Scavenging of chemokines by multiarmed poly(ethylene glycol)‐glycosaminoglycan (starPEG‐GAG) hydrogels has recently been shown to support regeneration in a diabetic mouse chronic skin ...
Lucas Schirmer, Passant Atallah, Uwe Freudenberg, Carsten Werner   +3 more
doaj   +1 more source

Medical application of glycosaminoglycans: a review

Journal of Tissue Engineering and Regenerative Medicine, 2018
The characteristic molecular composition of the different glycosaminoglycans (GAGs) is related to their role as structural components and regulators of a multitude of functions of proteins, cells and tissues in the human body.
Alexander Köwitsch, Guoying Zhou, T. Groth   +2 more
semanticscholar   +1 more source

Influence of combined nitrate and fluoride intoxication on connective tissue disorders in rats gastric mucosa [PDF]

Archives of the Balkan Medical Union, 2019
Introduction. Certain regions in Europe and Ukraine have high concentration of fluorides in drinking waters. Highly developed agriculture can result in increased concentration of nitrates in ground and drinking waters. Therefore, their combined excessive
Oleh Y. AKIMOV, Arthur V. MISCHENKO, Vitalii O. KOSTENKO   +2 more
doaj   +1 more source

Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

Nature Microbiology, 2019
Clostridium difficile toxin A (TcdA) is a major exotoxin contributing to disruption of the colonic epithelium during C. difficile infection. TcdA contains a carbohydrate-binding combined repetitive oligopeptides (CROPs) domain that mediates its ...
Liang Tao, Songhai Tian, Jie Zhang, Zhuoming Liu, Lindsey R. Robinson-McCarthy, Shin-Ichiro Miyashita, D. Breault, R. Gerhard, S. Oottamasathien, S. Whelan, M. Dong   +10 more
semanticscholar   +1 more source