Results 21 to 30 of about 85,805 (344)

Roles of Proteoglycans and Glycosaminoglycans in Cancer Development and Progression

International Journal of Molecular Sciences, 2020
The extracellular matrix (ECM) spatiotemporally controls cell fate; however, dysregulation of ECM remodeling can lead to tumorigenesis and cancer development by providing favorable conditions for tumor cells.
Jinfen Wei, Meiling Hu, Kaitang Huang, Shudai Lin, H. Du   +4 more
semanticscholar   +1 more source

High sensitivity analysis of nanogram quantities of glycosaminoglycans using ToF-SIMS

Communications Chemistry, 2021
Glycosaminoglycans are an important class of carbohydrates, but pose substantial analytical challenges. Here ToF-SIMS combined with multivariate analysis distinguishes six classes of glycosaminoglycans, including distinguishing heparin samples from ...
Andrew L. Hook, John Hogwood, Elaine Gray, Barbara Mulloy, Catherine L. R. Merry   +4 more
doaj   +1 more source

Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus

Nature Communications, 2020
The human gut microbiota (HGM), which is critical to human health, utilises complex glycans as its major carbon source. Glycosaminoglycans represent an important, high priority, nutrient source for the HGM.
D. Ndeh, A. Baslé, H. Strahl, E. Yates, Urszula L McClurgg, B. Henrissat, N. Terrapon, A. Cartmell   +7 more
semanticscholar   +1 more source

Vascular Dysfunction in Malaria: Understanding the Role of the Endothelial Glycocalyx

Frontiers in Cell and Developmental Biology, 2021
Malaria caused by Plasmodium falciparum results in over 400,000 deaths annually, predominantly affecting African children. In addition, non-falciparum species including vivax and knowlesi cause significant morbidity and mortality. Vascular dysfunction is
Margaret A. Bush, Nicholas M. Anstey, Tsin W. Yeo, Tsin W. Yeo, Tsin W. Yeo, Salvatore M. Florence, Donald L. Granger, Esther D. Mwaikambo, J. Brice Weinberg   +8 more
doaj   +1 more source

The NagY regulator: A member of the BglG/SacY antiterminator family conserved in Enterococcus faecalis and involved in virulence

Frontiers in Microbiology, 2023
Enterococcus faecalis is a commensal bacterium of the gastrointestinal tract but also a major nosocomial pathogen. This bacterium uses regulators like BglG/SacY family of transcriptional antiterminators to adapt its metabolism during host colonization ...
Diane Soussan, Diane Soussan, Marine Salze, Marine Salze, Pierre Ledormand, Pierre Ledormand, Nicolas Sauvageot, Nicolas Sauvageot, Amine Boukerb, Amine Boukerb, Amine Boukerb, Olivier Lesouhaitier, Olivier Lesouhaitier, Gwennaele Fichant, Alain Rincé, Alain Rincé, Yves Quentin, Cécile Muller, Cécile Muller   +18 more
doaj   +1 more source

Glycosaminoglycans and the peritoneaum [PDF]

Nephrology, 2002
SUMMARY: The introduction of peritoneal dialysis (PD) over two decades ago has allowed us to manipulate the peritoneal membrane to perform as a continuous dialysing organ. to maximize the efficacy of solute transport and waste removal, conventional PD fluids require unphysiological concentrations of glucose to provide the osmotic drive, lactate to ...
Yung, S, Chan, TM
openaire   +4 more sources

Evaluation of urinary glycosaminoglycans and matrix metalloproteinase-7 in lung cancer patients

Egyptian Journal of Chest Disease and Tuberculosis, 2013
Lung cancer accounts for one-third of all cancer-related deaths worldwide. Glycosaminoglycans and matrix metalloproteinase-7 (MMP-7) have been found to be involved in cancer.
Enas Samir Nabih, Mohamed Ali El Sayed
doaj   +1 more source

Glycosaminoglycans and Their Mimetics [PDF]

Molecules, 2016
Glycosaminoglycans (GAGs) are linear, polyanionic polysaccharides that are ubiquitous on the mammalian cell surface and in the extracellular matrix and are generally found attached to a protein core as part of a proteoglycan.[...]
openaire   +4 more sources

Natural Presentation of Glycosaminoglycans in Synthetic Matrices for 3D Angiogenesis Models

Frontiers in Cell and Developmental Biology, 2021
Glycosaminoglycans (GAGs) are long, linear polysaccharides that occur in the extracellular matrix of higher organisms and are either covalently attached to protein cores, as proteoglycans or in free form.
Cornelia Zapp, Cornelia Zapp, Patricia Mundinger, Patricia Mundinger, Heike Boehm, Heike Boehm   +5 more
doaj   +1 more source

HIGH LEVEL OF GLYCOSAMINOGLYCANS OF BLOOD SERUM AS AN INDEPENDENT PREDICTOR OF THE DEVELOPING PERITONEUM ADHESIVE DISEASE

Креативная хирургия и онкология, 2017
Peritoneal commissures is the phenomenon of adhesions formation with apparent symptom group of violations in functioning of the gastrointestinal tract and small pelvis.
I. F. Sufiyarov, A. G. Khasanov, M. A. Nurtdinov, A. V. Samorodov, G. R. Jamalova   +4 more
doaj   +1 more source