Results 21 to 30 of about 52,449 (293)
Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]
International Journal of Molecular Sciences, 2019 Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans. They are present not only on the cell surface, but also in the intracellular milieu and extracellular matrix.
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Brain and Behavior, 2020 Introduction Spinal cord injuries are devastating, with many complications beyond paralysis and loss of sensory function. Although spinal cord regeneration can revolutionize treatment for spinal cord injuries, the goal has not yet been achieved.
Alexander Lu +2 more
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Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing
Advanced Science, 2021 Excessive inflammation often impedes the healing of chronic wounds. Scavenging of chemokines by multiarmed poly(ethylene glycol)‐glycosaminoglycan (starPEG‐GAG) hydrogels has recently been shown to support regeneration in a diabetic mouse chronic skin ...
Lucas Schirmer +3 more
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Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle
Clinics, 2010 OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI ...
Jairo Jose Matozinho Cubas +5 more
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Influence of combined nitrate and fluoride intoxication on connective tissue disorders in rats gastric mucosa [PDF]
Archives of the Balkan Medical Union, 2019 Introduction. Certain regions in Europe and Ukraine have high concentration of fluorides in drinking waters. Highly developed agriculture can result in increased concentration of nitrates in ground and drinking waters. Therefore, their combined excessive
Oleh Y. AKIMOV +2 more
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Bioinformatics of glycosaminoglycans
Perspectives in Science, 2017 SummaryCell surface heparan sulfates modulate many signalling pathways by binding growth factors and growth factor receptors. Expressed in a spatially and temporally regulated manner, these highly sulfated polysaccharides play important roles in all aspects of animal physiology.
Han Hu +4 more
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Glycosaminoglycan–Protein Interactions: The First Draft of the Glycosaminoglycan Interactome [PDF]
Journal of Histochemistry & Cytochemistry, 2020 The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate, heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides. Except for hyaluronan, they are sulfated to various extent, and covalently attached to proteins to form proteoglycans.
Sylvain D. Vallet +2 more
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Norfloxacin-Loaded Electrospun Scaffolds: Montmorillonite Nanocomposite vs. Free Drug
Pharmaceutics, 2020 Infections in nonhealing wounds remain one of the major challenges. Recently, nanomedicine approach seems a valid option to overcome the antibiotic resistance mechanisms.
Angela Faccendini +10 more
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Current Issues in Molecular Biology, 2022 Chondroitin sulphate (CS) is one of the most predominant glycosaminoglycans (GAGs) available in the extracellular matrix of tissues. It has many health benefits, including relief from osteoarthritis, antiviral properties, tissue engineering applications,
Zannat Urbi +3 more
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Proton Conductivity of Glycosaminoglycans [PDF]
PLOS ONE, 2018 AbstractProton (H+) conductivity is important in many natural phenomena including oxidative phosphorylation in mitochondria and archea, uncoupling membrane potentials by the antibiotic Gramicidin, and proton actuated bioluminescence in dinoflagellate.
Selberg, John +2 more
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