Results 121 to 130 of about 39,910 (236)

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Megalin in normal tissues and carcinoma cells carries oligo/poly α2,8 deaminoneuraminic acid as a unique posttranslational modification [PDF]

, 2018
In rat kidney, megalin, a member of the low density lipoprotein receptor gene family, is the sole glycoprotein which carries oligo/poly α2,8 deaminoneuraminic acid (KDN) as a posttranslational modification. We have investigated immunoprecipitated megalin
Meier, Mirjam, Roth, Jürgen, Ziak, Martin   +2 more
core  

glycosidase

Citation: 'glycosidase' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09823 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

PECTIC GLYCOSIDASES OF ASPERGILLUS NIGER

The Journal of General and Applied Microbiology, 1954
Separation of GPG free from DPG in the manner of the adsorption of the latter on pulpified filter paper (Tab. 1), described in the previous report, is successfully achieved by fractional adsorption (Tab. 2). There is little difference between the properties of GPG thus obtained and of DPG. The optimum pH for the activity to liberate the reducing groups
openaire   +6 more sources

Azasugar Glycosidase Inhibitors: Useful Tools for Glycobiologists

CHIMIA, 1996
Glycosidase inhibitors are moving increasingly as potential agents for the treatment of diseases by altering glycosylation or catabolism of glycoconjugates.
Sylviane Picasso
doaj   +2 more sources

First Step Towards the Humanisation of Protein N‐Glycosylation in Chlamydomonas reinhardtii Through Heterologous Expression of α(1,2)‐Mannosidases

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2698-2700, April 2026.
C. Plasson, J. Balieu, P. Lerouge, M. Bardor, E. Mathieu‐Rivet   +4 more
wiley   +1 more source

Novel Quinoline- and Naphthalene-Incorporated Hydrazineylidene–Propenamide Analogues as Antidiabetic Agents: Design, Synthesis, and Computational Studies

Pharmaceuticals
Background: Type 2 diabetes has become a significant global health challenge. Numerous drugs have been developed to treat the condition, either as standalone therapies or in combination when glycemic control cannot be achieved with a single medication ...
Osama Alharbi, Wael H. Alsaedi, Mosa Alsehli, Saif H. Althagafi, Hussam Y. Alharbi, Yazeed M. Asiri, Ramith Ramu, Mohammed Al-Ghorbani   +7 more
doaj   +1 more source

Rapid O-glycan release from glycoproteins using a monolith-based glycosidase microreactor

Journal of Chromatography Open
Fast, efficient and simple selective O-glycan release methods are urgently needed for accurately analyzing O-glycans of therapeutic proteins or glycosylation-based biomarkers.
Bin Yang, Myriam Taverna, Cédric Y. Montanier, Zhengjin Jiang, N. Thuy Tran   +4 more
doaj   +1 more source

Isolation and characterization of a laminin-binding protein from rat and chick muscle. [PDF]

, 1988
A major laminin-binding protein (LBP), distinct from previously described LBPs, has been isolated from chick and rat skeletal muscle (Mr 56,000 and 66,000, respectively).
Frazer, KA, Hall, DE, Hann, BC, Reichardt, LF   +3 more
core  

In Situ Differential Analysis of α- and β-Glycosidase Activities in Lysosomes After Internalization Using Glucosylcerebroside-Based Liposomes. [PDF]

Int J Mol Sci
Wei Y, Kanie O.
europepmc   +1 more source