Quinoline- and Isoindoline-Integrated Polycyclic Compounds as Antioxidant, and Antidiabetic Agents Targeting the Dual Inhibition of α-Glycosidase and α-Amylase Enzymes [PDF]
Pharmaceuticals, 2023 Novel analogs of quinoline and isoindoline containing various heterocycles, such as tetrazole, triazole, pyrazole, and pyridine, were synthesized and characterized using FT-IR, NMR, and mass spectroscopy, and their antioxidant and antidiabetic activities
Mohammed Al-Ghorbani +3 more
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Water Caltrop (Trapa quadrispinosa Roxb.) Husk Improves Oxidative Stress and Postprandial Blood Glucose in Diabetes: Phenolic Profiles, Antioxidant Activities and α-Glycosidase Inhibition of Different Fractions with In Vitro and In Silico Analyses [PDF]
Antioxidants, 2022 The aim of this study was to investigate the phenolic profiles, antioxidant activities and α-glycosidase inhibitory activities of three different phenolic fractions from water caltrop (Trapa quadrispinosa Roxb.) husk and to further explore the ...
Yuanyue Zhang +5 more
doaj +2 more sources
Some old 2-(4-(Aryl)- thiazole-2-yl)-3a,4,7,7a-tetrahydro-1H-4,7-tethanoisoindole-1,3(2H)-dione derivatives: Synthesis, inhibition effects and molecular docking studies on Aldose reductase and α-Glycosidase [PDF]
Cumhuriyet Science Journal, 2021 Utilizing the simple chromatic techniques, Aldose reductase (AR) was derived from sheep liver. In addition, α-glycosidase from Saccharomyces cerevisiae was used as the enzyme.
Burak Tüzün +7 more
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Novel Antioxidants and α-Glycosidase and Protein Tyrosine Phosphatase 1B Inhibitors from an Endophytic Fungus Penicillium brefeldianum F4a [PDF]
Journal of Fungi, 2021 Oxidative stress plays a very important role in the progression of diabetes and its complications. A therapeutic agent that is both antidiabetic and antioxidant would be the preferred choice for the treatment of diabetes.
Yan Bai +4 more
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A Surface Acoustic Wave (SAW)-Based Lab-on-Chip for the Detection of Active α-Glycosidase [PDF]
Biosensors, 2022 Enzyme detection in liquid samples is a complex laboratory procedure, based on assays that are generally time- and cost-consuming, and require specialized personnel.
Mariacristina Gagliardi +7 more
doaj +2 more sources
Polyphenols Content and In Vitro α-Glycosidase Activity of Different Italian Monofloral Honeys, and Their Effect on Selected Pathogenic and Probiotic Bacteria [PDF]
Microorganisms, 2021 We evaluated the polyphenol content and the α-glucosidase activity exhibited by different monofloral honeys of Italian origin. Their capacity to act on different pathogenic (Acinetobacter baumannii, Escherichia coli, Listeria monocytogenes, Pseudomonas ...
Florinda Fratianni +7 more
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Chiliadenus iphionoides: From chemical profiling to anticancer, antioxidant, α-amylase, and α-glycosidase activities. [PDF]
PLoS ONERecently, essential oils (EOs) have garnered attention for their biological properties as a source of natural compounds with anticancer, antibacterial, and antioxidant effects.
Odey Bsharat +3 more
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Design and Synthesis of Phenoxymethybenzoimidazole Incorporating Different Aryl Thiazole-Triazole Acetamide Derivatives as α-Glycosidase Inhibitors [PDF]
Molecular Diversity, 2022 Bagher Larijani +2 more
exaly +2 more sources
Quality Parameters, Metabolomics Profile, and Biology Activities of Some Honey (Apis mellifera) Samples Obtained from Pretoria and Johannesburg, South Africa [PDF]
MetabolitesBackground/Objectives: Honey is a natural product with important nutritional and biological properties. This study aimed to comprehensively evaluate honey samples with regard to physicochemical quality, safety, antioxidant capacity, and enzyme inhibitory
Münire Turhan
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Frontiers in Chemistry, 2021 α-Glycosidase inhibitors could inhibit the digestion of carbohydrates into glucose and promote glucose conversion, which have been used for the treatment of type 2 diabetes.
Shan-Kui Liu +13 more
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