Precision Profiling of α‐1,4‐ Versus α‐1,6‐Glycosidase Activity Through Synthetic Linear and Branched Glycogen Tetramers Using Cyclic Ion Mobility Mass Spectrometry and High‐Performance Liquid Chromatography‐Mass Spectrometry [PDF]
Synthesis of glycogen‐like tetrasaccharides allowed the design of an integrated HILIC‐MS/cyclic ion mobility MS workflow to characterize glycosidase specificity. HsGDE selectively hydrolyzed α‐1,6 branches, whereas yeast α‐1,4‐glucosidase preferentially cleaved α‐1,4 linkages, and the rice enzyme showed broader regioisomeric activity.
Delphine Carry +12 more
openalex +2 more sources
Antidiabetic Potential: Effect of Resorcinol on α-Glycosidase and α-Amylase Enzymes
The vast majority of the carbohydrates in the biomolecule class areformed by photosynthesis using sunlight. One of the important enzymes in thisclass is α-glycosidase. This enzyme converts complex carbohydrates tomonosaccharides.
Fevzi Topal
doaj +2 more sources
A Machine Learning Approach to Study Glycosidase Activities from Bifidobacterium
This study aimed to recover metagenome-assembled genomes (MAGs) from human fecal samples to characterize the glycosidase profiles of Bifidobacterium species exposed to different prebiotic oligosaccharides (galacto-oligosaccharides, fructo ...
Carlos Sabater +2 more
doaj +2 more sources
Azasugar Glycosidase Inhibitors: Useful Tools for Glycobiologists [PDF]
Glycosidase inhibitors are moving increasingly as potential agents for the treatment of diseases by altering glycosylation or catabolism of glycoconjugates.
Sylviane Picasso
doaj +4 more sources
Substrate scope of ancestral versus modern family-1 glycosidases. [PDF]
Gutierrez-Rus LI +11 more
europepmc +2 more sources
Pseudouridine Monophosphate Glycosidase: A New Glycosidase Mechanism [PDF]
Pseudouridine (Ψ), the most abundant modification in RNA, is synthesized in situ using Ψ synthase. Recently, a pathway for the degradation of Ψ was described [Preumont, A., Snoussi, K., Stroobant, V., Collet, J. F., and Van Schaftingen, E. (2008) J. Biol. Chem. 283, 25238-25246].
Siyu, Huang +3 more
openaire +2 more sources
Crystal structure of Legionella pneumophila glycosidase effector LegY. [PDF]
Chen J, Li F, Wang SY, Chen TT.
europepmc +3 more sources
Modular Molecular Design and Self-Assembled Nanostructures of Saccharide‑Appended Cyclic Dipeptides for Glycosidase‑Responsive Supramolecular Hydrogels. [PDF]
Sugiura S +6 more
europepmc +2 more sources
Discovery of Novel Glycosidase-Derived Cell-Penetrating Peptides Encoded by Human Gut Commensals. [PDF]
Post SE +7 more
europepmc +3 more sources
This review covers the literature in the past 15 years on glycosidase inhibitors lacking a basic nitrogen (for example iminosugars/azasugars) with a focus on natural terpenoids, and mono- and polycyclic aromatic hydrocarbons.
Campkin, David +9 more
core +1 more source

