Results 161 to 170 of about 10,037 (210)

Isolation of a Novel Low-Temperature-Active and Organic-Solvent-Stable Mannanase from the Intestinal Metagenome of Hermetia illucens. [PDF]

Int J Mol Sci
Kim DG, Lee CM, Lee YS, Yoon SH, Kim SY.
europepmc   +1 more source

A dual-functional substrate for quantitation of substrate levels and GCase activity in living cells. [PDF]

RSC Chem Biol
Tiet B, Zhu S, Chen X, Anastasi N, See NW, Deen MC, Harde E, Vocadlo DJ.   +7 more
europepmc   +1 more source

Hacking the immune system: plant immune protease engineering for crop protection. [PDF]

J Exp Bot
Schuster M, Ciattoni AL, van der Hoorn RAL.   +2 more
europepmc   +1 more source

Transcriptome sequencing reveals Vmplc1 involved in regulating the pathogenicity of Valsa Mali under low temperature induction. [PDF]

BMC Genomics
Meng X, Dong Y, Yin J, Gao S, Liu A, Li D, Guo J, Li B, Dai P, Wang Y, Hu T, Cao K, Wang S.   +12 more
europepmc   +1 more source

Strategies for developing carbohydrates as glycoside hydrolase inhibitors

, 2020
The cleavage of the glycosidic bond in glycoconjugates is an important activity in biological systems. The enzymes catalyzing this activity are termed as “glycoside hydrolases” (GH). About 1% of the genome in organisms are encoded by GHs. Researchers have put in tremendous amount of effort in understanding the mechanism of GHs and the effect of their ...
Radhika Thanvi, Sunayana Kapil, Steven J. Sucheck   +2 more
openalex   +2 more sources

Mixed-Linkage Cellooligosaccharides: A New Class of Glycoside Hydrolase Inhibitors

ChemBioChem, 2001
A new class of inhibitors for beta-D-glycoside hydrolases, in which a single alpha-(1-->4)-glycosidic bond is incorporated into an otherwise all-beta-(1-->4)-linked oligosaccharide, is described. Such mixed beta/alpha-linkage cellooligosaccharides are not transition-state mimics, but instead are capable of utilising binding energy from numerous ...
Sébastien Fort, Annabelle Varrot, Martin Schülein, Sylvain Cottaz, Hugues Driguez, G.J. Davies   +5 more
  +5 more sources

Recent advances in glycoside hydrolase family 20 and 84 inhibitors: Structures, inhibitory mechanisms and biological activities

Bioorganic Chemistry, 2023
Glycoside hydrolase family 20 (GH20) β-N-acetyl-d-hexosaminidase (Hex) catalyzes the cleavage of glycosidic linkages in glycans, glycolipids and glycoproteins, and is involved in glycoprotein modification, metabolism of glycoconjugate and the degradation of chitin in fungal cell walls and arthropod exoskeletons. GH84 O-β-N-acetyl-d-glucosaminidase (OGA)
Xi Jiang, Qing Yang
openalex   +3 more sources

A GLYCOSIDE-HYDROLASE INHIBITOR IN TREATMENT OF DUMPING SYNDROME

The Lancet, 1979
BAY g 5421, a glycoside-hydrolase inhibitor, produced symptomatic improvement in ten patients with the dumping syndrome. 100 mg BAY g 5421, given before a 50 g sucrose meal, produced pronounced attenuation of both hyperglycaemic and hypoglycaemic phases of plasma glucose levels; and it greatly reduced the rise in plasma levels of gastric inhibitory ...
J. C. McLoughlin, K. D. Buchanan, M.J. Alam   +2 more
openalex   +3 more sources

ChemInform Abstract: Glycoside Hydrolases: Mechanistic Information from Studies with Reversible and Irreversible Inhibitors

ChemInform, 1991
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
G. Legler
openalex   +2 more sources

Glycoside Hydrolases: Mechanistic Information from Studies with Reversible and Irreversible Inhibitors

, 1990
Publisher Summary This chapter discusses the results of the studies that permit some generalizations on the catalytic mechanism of glycoside hydrolases from widely differing sources and with different sugar and aglycon specificities and that have become available over the past 15 years.
Günter Legler
openalex   +3 more sources