Results 151 to 160 of about 162,319 (334)
Biochemical Journal, 2015 Carbohydrates are ubiquitous in Nature and play vital roles in many biological systems. Therefore the synthesis of carbohydrate-based compounds is of considerable interest for both research and commercial purposes. However, carbohydrates are challenging,
Bastien Bissaro +3 more
semanticscholar +1 more source
The FEBS Journal, EarlyView.The multidomain glycosidase MDG from the hyperthermophilic euryarchaeon Thermococcus sp. contains five protein domains: three catalytic domains (GH5, GH12‐1, and GH12‐2) and two cellulose‐binding modules (CBM2). In this study, the GH12‐1 and GH12‐2 domains were individually purified and biochemically characterized.
Kseniya S. Zayulina +11 more
wiley +1 more source
Hierarchical hydropathic evolution of influenza glycoproteins (N2, H3, A/H3N2) under relentless vaccination pressure [PDF]
arXiv, 2013 Hemagglutinin (HA) and neuraminidase (NA) are highly variable envelope glycoproteins. Here hydropathic analysis, previously applied to quantify common flu (H1N1) evolution (1934-), is applied to the evolution of less common but more virulent (avian derived) H3N2 (1968-), beginning with N2.
arxiv
Electrostatic potential as a reactivity scoring function in computer‐assisted enzyme engineering
The FEBS Journal, EarlyView.We present a computational metric that quantifies the electrostatic complementarity of enzymes to the charge distribution of substrates at the transition state. Implemented in BindScan, this metric accurately predicts functionally relevant mutations in glycoside hydrolases.
Aitor Vega, Antoni Planas, Xevi Biarnés
wiley +1 more source
Nanophotonics and DNA: New approaches [PDF]
arXiv, 2014 The aim of the present work is spectroscopic and thermodynamic study of DNA catalytic properties in the following processes: a) redox; b) formation of inter-strand cross-links; c) performing of photo-dynamic effects; d) nanoscale resonance radiationless electron excitation energy transfer.
arxiv
Hole hopping through tyrosine/tryptophan chains protects proteins from oxidative damage [PDF]
, 2015 Living organisms have adapted to atmospheric dioxygen by exploiting its oxidizing power while protecting themselves against toxic side effects. Reactive oxygen and nitrogen species formed during oxidative stress, as well as high-potential reactive ...
Gray, Harry B., Winkler, Jay R.
core +1 more source
Molecular mechanisms of processive glycoside hydrolases underline catalytic pragmatism. [PDF]
Biochem Soc Trans, 2023 Hrmova M, Schwerdt JG.
europepmc +1 more source
Scientific Reports, 2017 Cellulolytic enzymes capable of hydrolyzing plant biomass are secreted by microbial cells specifically in response to the carbon substrate present in the environment.
Nandita Pasari +8 more
semanticscholar +1 more source
Journal of Integrative Plant Biology, EarlyView.The rice pollen‐specific receptor‐like kinases OsPRK1, OsPRK2, and OsPRK3 play a crucial role in reactive oxygen species (ROS)‐mediated pollen hydration and germination. Triple mutants display male sterility due to decreased ROS levels and impaired pollen hydration, and their germination phenotype can be partially restored by exogenous application of ...
Eui‐Jung Kim +9 more
wiley +1 more source
Allylic Carbocyclic Inhibitors Covalently Bind Glycoside Hydrolases. [PDF]
JACS Au, 2023 Grayfer TD +11 more
europepmc +1 more source