Results 221 to 230 of about 35,445 (258)

Advancing Chemoenzymatic Synthesis and Covalent Immobilization of a Comprehensive Ganglio-glycosphingolipid Library Enables Functional Multiplex Bead Assays. [PDF]

J Am Chem Soc
Gucchait A, Fu J, Zhang L, Agrahari AK, Zheng Z, Yang X, Yu H, Yang X, Varki A, Chen X.   +9 more
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Gut Microbiome and Metabolome Signatures Associated with Heat Tolerance in Dairy Cows. [PDF]

Microorganisms
Li M, Chen P, Liu C, Wang S, Zhang H, Li J, Karrow NA, Mao Y, Yang Z.   +8 more
europepmc   +1 more source

Functional analysis of the effect of isoimperatorin on human acute monocytic leukemia at the transcriptome level. [PDF]

Oncol Lett
Yin R, Xu R, Ming H, Song J.
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Structural and immunochemical characterization of glycosylinositol phosphorylceramides from Aspergillus fumigatus: effect of glycosphingolipid synthesis inhibitors on pathogenic fungi

, 2006
Luciana Lopes [UNIFESP] Guimaraes
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Glycosphingolipids

2021
Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology.In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this ...
Elena Chiricozzi, Massimo Aureli, Laura Mauri, Erika Di Biase, Giulia Lunghi, Maria Fazzari, Manuela Valsecchi, Emma Veronica Carsana, Nicoletta Loberto, Alessandro Prinetti, and Sandro Sonnino   +10 more
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Biochemistry of glycosphingolipid degradation

Clinica Chimica Acta, 1997
Glycosphingolipids (GSLs) form cell-type-specific patterns on the surface of eukaryotic cells. Degradation of GSLs requires endocytotic membrane flow of plasma membrane-derived GSLs into the lysosomes as the digesting organelles. Recent research focused on the mechanisms leading to selective membrane degradation in the lysosomes and on the mechanism ...
K, Sandhoff, T, Kolter
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Glycosphingolipids govern gene expression

Glycoconjugate Journal, 2003
To elucidate the biological significance of the lactosylceramide (LacCer) branching in glycosphingolipid (GSL) biosynthesis, we established ganglioside GM3- and lactosylsulfatide SM3-reconstituted cells by introducing the GM3 synthase gene and the sulfotransferase gene, respectively.
Jin-ichi, Inokuchi, Kazuya, Kabayama, Satoshi, Uemura, Yasuyuki, Igarashi   +3 more
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Glycosphingolipids in membrane architecture

Journal of Supramolecular Structure, 1977
AbstractAs part of a program to investigate the behavior and interactions of glycolipids in biological membranes we have synthesized spin‐labeled derivatives of 2 families of carbohydrate‐bearing ceramides (glycosphingolipids): simple neutral glycolipids and gangliosides.
F J, Sharom, C W, Grant
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Glycosphingolipids and Insulin Resistance

2011
Glycosphingolipids are structural membrane components, residing largely in the plasma membrane with their sugar-moieties exposed at the cell's surface. In recent times a crucial role for glycosphingolipids in insulin resistance has been proposed. A chronic state of insulin resistance is a rapidly increasing disease condition in Western and developing ...
Aerts, J.M., Boot, R.G., van Eijk, M., Groener, J., Bijl, N., Lombardo, E., Bietrix, F.M., Dekker, N., Groen, A.K., Ottenhof, M., Roomen, C., Aten, J., Serlie, M., Langeveld, M., Wennekes, T., Overkleeft, H.S.   +15 more
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Glycosphingolipids and insulin resistance

Progress in Lipid Research, 2009
Obesity is associated with an increased risk for insulin resistance, a state characterized by impaired responsiveness of liver, muscle and adipose tissue to insulin. One class of lipids involved in the development of insulin resistance are the (glyco)sphingolipids. Ceramide, the most simple sphingolipid, directly inhibits phosphorylation of the insulin
Mirjam, Langeveld, Johannes M F G, Aerts
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