Results 21 to 30 of about 54,595 (236)

Synthesis and glycosidation of building blocks of D-altrosamine

open access: yesFrontiers in Chemistry, 2022
Presented herein is a streamlined synthesis of building blocks of a rare sugar D-altrosamine. Also investigated was the glycosylation of different glycosyl acceptors with differentially protected altrosamine donors.
Mariya Novakova   +4 more
doaj   +1 more source

Regenerative Glycosylation [PDF]

open access: yesThe Journal of Organic Chemistry, 2017
Previously, we communicated 3,3-difluoroxindole (HOFox)-mediated glycosylations wherein 3,3-difluoro-3H-indol-2-yl (OFox) imidates were found to be key intermediates. Both the in situ synthesis from the corresponding glycosyl bromides and activation of the OFox imidates could be conducted in a regenerative fashion.
Yashapal Singh   +4 more
openaire   +2 more sources

A method for the quantitative determination of neutral glycosphingolipids in urine sediment

open access: yesJournal of Lipid Research, 1970
A method is described for the isolation and quantitation of six neutral glycosyl ceramides from human urinary sediment. Total lipids were extracted from sediments of 24-hr urine collections, and the glycosyl ceramides were isolated by silicic acid column
R.J. Desnick, C.C. Sweeley, W. Krivit
doaj   +1 more source

Effective Synthesis of Nucleosides Utilizing O-Acetyl-Glycosyl Chlorides as Glycosyl Donors in the Absence of Catalyst: Mechanism Revision and Application to Silyl-Hilbert-Johnson Reaction

open access: yesMolecules, 2017
An effective synthesis of nucleosides using glycosyl chlorides as glycosyl donors in the absence of Lewis acid has been developed. Glycosyl chlorides have been shown to be pivotal intermediates in the classical silyl-Hilbert-Johnson reaction.
Chengyuan Liang   +4 more
doaj   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

open access: yesAngewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra   +9 more
wiley   +2 more sources

Glycosyl Formates: Glycosylations with Neighboring-Group Participation

open access: yesMolecules, 2022
Protected 2-O-benzyolated glycosyl formates were synthesized in one-step from the corresponding orthoester using formic acid as the sole reagent.
Liang Yang, Christian Marcus Pedersen
doaj   +1 more source

Analysis and glycosyl composition of the exopolysaccharide isolated from submerged fermentation of Ganoderma lucidum CG144

open access: yesActa Societatis Botanicorum Poloniae, 2014
The evaluation of glycosyl composition is an essential step to guide future research designs applied in bioactivity. In the same way, the unexplored potential bioactivity of exopolysaccharide from Ganoderma lucidum is huge.
Rosália Rubel   +9 more
doaj   +1 more source

New technique for enzymic hydrolysis of glycosphingolipids

open access: yesJournal of Lipid Research, 1969
A method is described for the study of glycosyl ceramide glycosyl hydrolases. Problems arising from the limited solubility of glycosyl ceramides in aqueous media were overcome by coating the substrate on a filter paper disc that had been treated with ...
Glyn Dawson, Charles C. Sweeley
doaj   +1 more source

Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides

open access: yesNature Communications, 2020
O-glycosides and nucleosides are important biomolecules. Here, the authors developed a protocol for the synthesis of such molecules with a broad substrate scope using glycosyl ortho-(1-phenylvinyl)benzoates as glycosyl donors that allow for mild reaction
Penghua Li   +8 more
doaj   +1 more source

Activation of Thioglycosides with Copper(II) Bromide

open access: yesMolecules, 2022
Reported herein is a new protocol for glycosidation of alkyl and aryl thioglycosides in the presence of copper(II) bromide. While the activation with CuBr2 alone was proven suitable for reactive glycosyl donors, the activation of less reactive donors was
Faranak Pooladian   +2 more
doaj   +1 more source

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