Reassessment of Acarbose as a Transition State Analogue Inhibitor of Cyclodextrin Glycosyltransferase [PDF]
, 1998 The binding of several different active site mutants of Bacillus circulans cyclodextrin glycosyltransferase to the inhibitor acarbose has been investigated through measurement of Ki values.
Dijkstra, Bauke W., +5 more
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ELECTROPHORESIS, 2018 AbstractThe change of cellular glycosylation is one of the key events in malignant transformation and neoplastic progression, and tumor‐related glycosylation alterations are promising targets in both tumor diagnosis and therapy. Both malignant transformation and neoplastic progression are the consequence of gene expression alterations and alterations ...
Krešimir Pavelić +3 more
openaire +4 more sources
GASdb: a large-scale and comparative exploration database of glycosyl hydrolysis systems
BMC Microbiology, 2010 Background The genomes of numerous cellulolytic organisms have been recently sequenced or in the pipeline of being sequenced. Analyses of these genomes as well as the recently sequenced metagenomes in a systematic manner could possibly lead to ...
Xu Ying, Chen Huiling, Zhou Fengfeng
doaj +1 more source
Novel glycosyl prodrug of RXP03 as MMP-11 prodrug: design, synthesis and virtual screening
BMC Chemistry, 2023 Like most phosphinic acids, the potent and selective RXP03 inhibitor of different MMPs exhibited moderate absorption and low bioavailability, which impaired its use. In an unprecedented attempt, we present an interesting synthetic approach to a new class
Moaz M. Abdou +3 more
doaj +1 more source
Draft Genome Sequences of Salmonella enterica Serovar Typhimurium LT2 with Deleted Chitinases That Are Emerging Virulence Factors. [PDF]
, 2017 Chitinases are glycosyl hydrolases that catalyze the hydrolysis of the β-1,4 linkages in complex carbohydrates and those that contain GlcNAc. These enzymes are considered emerging virulence factors during infection because the host glycan changes.
Arabyan, Narine +2 more
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Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: Relevance of their surface active properties and of the type of emulsifier [PDF]
, 2015 The antioxidant activity of gallic acid and a series of alkyl gallates (C4-C18) and glycosylated alkyl gallates (C4-C18) on fish oil-in-water emulsions was studied.
González, M. Jesús +4 more
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Advanced Synthesis &Catalysis, EarlyView.Abstract Glycosyl furans represent versatile chiral platform molecules that can be readily accessed via the Garcia Gonzalez reaction. Herein, we report a dearomative, intramolecular bromoetherification of carbohydrate‐derived glycosyl furans to generate enantiopure 6‐bromo‐furo[3,2‐b]furans in up to 69% yield. The method employs N‐Br aromatic amides as
William J. Berkey +5 more
wiley +1 more source
Matching Glycosyl Donor Reactivity to Sulfonate Leaving Group Ability Permits SN2 Glycosylations
Journal of the American Chemical Society, 2019 Here we demonstrate that highly β-selective glycosylation reactions can be achieved when the electronics of a sulfonyl chloride activator and the reactivity of a glycosyl donor hemiacetal are matched.
Ming-Hua Zhuo +3 more
semanticscholar +1 more source
Advanced Sustainable Systems, EarlyView.This study explores the potential of locally harvested Phallusia mammillata, a tunicate usually discarded as waste from mussles farming as a viable source for producing various high‐grade cellulose derivatives in the form of nanofibrils (NFC) and nanocrystals (CNC). Abstract Ascidians are ubiquitous filter‐feeding marine invertebrates, the only animals
Andrea Riccioni +6 more
wiley +1 more source
Biochemical Characterization of Diamide Inhibitors with N-acetylglucosaminidases LytG from Bacillus subtilis [PDF]
, 2016 In recent years the frequency of antibiotic resistance has been on the rise creating a need for antibiotic development with specific and lethal targets.
Phelan, Drew
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