Results 111 to 120 of about 321,819 (263)
The functional and structural properties of enzymatic hydrolysis and glycosylation synergistic modified ovalbumin (OVA) were investigated. The results showed that hydrolysis and glycosylation had synergetic effects on emulsifying and foaming properties ...
Lili Liu+4 more
doaj +1 more source
Glycosylation in the tumor immune response: the bitter side of sweetness
Glycosylation is the most structurally diverse form of post-translational modification (PTM) of proteins that affects a myriad of cellular processes. As a pivotal regulator of protein homeostasis, glycosylation notably impacts the function of proteins ...
Cao Yuting, Yi Wen, Zhu Qiang
doaj +1 more source
Cellular glycosylation processes are vital to cell functioning. In malignant cells, they are profoundly altered. We used time-course gene expression data from the NCI-60 cancer cell lines treated with 11 antitumor agents to analyze expression changes of ...
Julia Krushkal+5 more
doaj +1 more source
Primary structural requirements for N‐glycosylation of peptides in rat liver [PDF]
Ernst Bause, Harald Hettkamp
openalex +1 more source
Predicting O-GlcNAcylation Sites in Mammalian Proteins with Transformers and RNNs Trained with a New Loss Function [PDF]
Glycosylation, a protein modification, has multiple essential functional and structural roles. O-GlcNAcylation, a subtype of glycosylation, has the potential to be an important target for therapeutics, but methods to reliably predict O-GlcNAcylation sites had not been available until 2023; a 2021 review correctly noted that published models were ...
arxiv
In silico evaluation of the role of Fab glycosylation in cetuximab antibody dynamics
IntroductionN-glycosylation is a post-translational modification that is highly important for the development of monoclonal antibodies (mAbs), as it regulates their biological activity, particularly in terms of immune effector functions.
Simona Saporiti+6 more
doaj +1 more source
Interference with glycosylation of glycoproteins. Inhibition of formation of lipid-linked oligosaccharides in vivo [PDF]
R. Datema, Ralph Τ. Schwarz
openalex +1 more source
Formation of 2-Deoxyglucose-Containing Lipid-Linked Oligosaccharides. Interference with Glycosylation of Glycoproteins [PDF]
R. Datema, Ralph Τ. Schwarz
openalex +1 more source
Glycosylation of vesicular stomatitis virus glycoprotein in virus-infected HeLa cells [PDF]
Lee Hunt, Donald F. Summers
openalex +1 more source