Predicting O-GlcNAcylation Sites in Mammalian Proteins with Transformers and RNNs Trained with a New Loss Function [PDF]
arXivGlycosylation, a protein modification, has multiple essential functional and structural roles. O-GlcNAcylation, a subtype of glycosylation, has the potential to be an important target for therapeutics, but methods to reliably predict O-GlcNAcylation sites had not been available until 2023; a 2021 review correctly noted that published models were ...
arxiv
Synthesis of Glucosyl-Dolichol Derivatives in Bakers' Yeast and Their Role in Protein Glycosylation [PDF]
, 1977 Armando J. Parodi
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Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 137-147, January 2023., 2023 On the basis of current research it was suggested that FPG have anti‐hyperlipidemic potential. Still, the mechanism of actions of FPG as anti‐hyperlipidemic and other therapeutic potential have yet to be explored. Abstract Flaxseed polysaccharide gum (FPG) was extracted through the ultrasound‐assisted process using water as a solvent with a yield ...
Muhammad Nadeem Akhtar +8 more
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Primary structural requirements for N‐glycosylation of peptides in rat liver [PDF]
, 1979 Ernst Bause, Harald Hettkamp
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Improving outcomes in intensified processing via optimization of the cell line development workflow
Biotechnology Progress, EarlyView.Abstract As the industry continues to explore the benefits of continuous and intensified manufacturing, it is important to assure that the cell line development (CLD) workflows in practice today are well suited to generate clones that meet the unique challenges associated with these processes. Most cell lines used in intensified processes are currently
Vincent Balassi +8 more
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Identification of compounds from chufa (Eleocharis dulcis) peels by widely targeted metabolomics
Food Science &Nutrition, Volume 11, Issue 1, Page 545-554, January 2023., 2023 The big Chinese water chestnut (BCWC) and small Chinese water chestnut (SCWC) peels using ultraperformance liquid chromatography/mass spectrometry (UPLC/MS)‐based metabolomics analysis. A total of 321 significant metabolites, including 90 flavonoids, 25 phenylpropanoids, and 33 organic acids and derivatives, were identified/annotated from BCWC and SCWC.
Guanli Li +4 more
wiley +1 more source
ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA
Redox Biology, 2022 N-glycosylation and disulfide bond formation are two essential steps in protein folding that occur in the endoplasmic reticulum (ER) and reciprocally influence each other.
Ersilia Varone +10 more
doaj
The role of glycosylation on the biosynthesis, degradation, and secretion of the acth‐β‐lipotropin common precursor and its peptide products [PDF]
, 1978 Y. Peng Loh, Harold Gainer
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