Results 131 to 140 of about 175,061 (321)

Glycosylation of the surface glycoprotein of Halobacterium salinarium via a cyclic pathway of lipid‐linked intermediates [PDF]

, 1978
Matthew F. Mescher, Jack L. Strominger
openalex   +1 more source

Blocking ITGA5 potentiates the efficacy of anti‐PD‐1 therapy on glioblastoma by remodeling tumor‐associated macrophages

Cancer Communications, EarlyView.
Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao, Ziwen Pan, Jiawei Qiu, Boyan Li, Yanhua Qi, Zijie Gao, Wei Qiu, Weijie Tang, Xiaofan Guo, Lin Deng, Gang Li, Hao Xue   +11 more
wiley   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

Protein glycosylation through dolichol derivatives in baker's yeast [PDF]

, 1976
Armando J. Parodi
openalex   +1 more source

LC‐DAD‐MSn and HR‐LC‐QTOF analysis of Ziziphus budhensis leaves and evaluation of their in vitro and in vivo biological activities

Chemistry &Biodiversity, Accepted Article.
Ziziphus budhensis is a species described in 2015 in Nepal poorly studied for its phytochemical composition and possible bioactivities. In this study, six extracts were obtained from Z. budhensis leaves using ultrasound assisted extraction with solvents in increasing polarity.
Samjhana Bharati, Binita Maharjan, Timila Shrestha, Shyam Sharan Shrestha, Stefania Sut, Hari Prasad Devkota, Ram Lal Swagat Shrestha, Stefano Dall'Acqua   +7 more
wiley   +1 more source

The pathogenic c.1171A>G (p.Arg391Gly) and c.2359G>A (p.Val787Ile) ABCC6 variants display incomplete penetrance causing pseudoxanthoma elasticum in a subset of individuals

Human Mutation, Volume 43, Issue 12, Page 1872-1881, December 2022., 2022
Abstract ABCC6 promotes ATP efflux from hepatocytes to bloodstream. ATP is metabolized to pyrophosphate, an inhibitor of ectopic calcification. Pathogenic variants of ABCC6 cause pseudoxanthoma elasticum, a highly variable recessive ectopic calcification disorder.
Flora Szeri, Agnes Miko, Nastassia Navasiolava, Ambrus Kaposi, Shana Verschuere, Beatrix Molnar, Qiaoli Li, Sharon F. Terry, Federica Boraldi, Jouni Uitto, Koen van de Wetering, Ludovic Martin, Daniela Quaglino, Olivier M. Vanakker, Kalman Tory, Tamas Aranyi   +15 more
wiley   +1 more source

Antioxidants and Antidiabetic Potential of Polyphenolic Fractions and Crude Extracts of Rhus coriaria L. Fruit, Punica granatum L. Peel, and Terminalia catappa L. Leaves: In Vitro and In Vivo Evaluation

Chemistry &Biodiversity, EarlyView.
This graphical abstract represents the extraction, characterization, and biological evaluation of bioactive compounds derived from specific plant sources. The top section illustrates Rhus coriaria (sumac) fruit, Punica granatum (pomegranate) peel and Terminalia catappa (Indian almond) leaves', which are known for their rich phytochemical composition ...
Mudassir Nazir, Muhammad Abdul Haq, Syed Arsalan Ali, Syed Muhammad Ghufran Saeed, Muhammad Ali Ajmal, Muhammad Nisar, Taseer Ahmed Khan, Alexandros Tsoupras, Shahina Naz   +8 more
wiley   +1 more source

Transcriptomics as a predictor of biopharmaceutically favourable glycan profiles

Frontiers in Cell and Developmental Biology
N-glycosylation plays a crucial role in defining the pharmacological properties and efficacy of therapeutic proteins, commonly referred to as biologics. The inherent complexity and lack of a templated process in glycosylation leads to a wide variation in
Ben West, Pavlos Kotidis, Alena Istrate, Daniele Perna, Gary Finka, A. Jamie Wood, A. Jamie Wood, Daniel Ungar   +7 more
doaj   +1 more source

Stereoselective Total Synthesis of α‐Galacto‐Oligosaccharides Using Boron‐Mediated Aglycon Delivery and Evaluation of Their Immune‐Enhancing Activities

ChemBioChem, Accepted Article.
α‐Galacto‐oligosaccharides (α‐GOSs) are natural oligomeric saccharides found in plants that have garnered significant interest due to their indigestible nature and various biological activities. However, they often exist as inseparable mixtures, particularly long‐chain substances.
Jikun Meng, Moeri Sagawa, Kazunobu Toshima, Daisuke Takahashi   +3 more
wiley   +1 more source

Further studies on the effect of the collagen triple-helix formation on the hydroxylation of lysine and the glycosylations of hydroxylysine in chick-embryo tendon and cartilage cells [PDF]

, 1977
Aarne Oikarinen, Henrik Anttinen, Kari I. Kivirikko   +2 more
openalex   +1 more source