Results 131 to 140 of about 331,855 (331)
Peptide Hormone‐Mediated Regulation of Plant Development and Environmental Adaptability
Advanced Science, EarlyView.In this review, recent advances in understanding the roles of plant peptide hormones in regulating growth, reproduction, and environmental adaptability are systematically summarized. It further elucidates the challenges in studying these peptides, such as their low abundance, functional redundancy, and complex signaling mechanisms, and highlights their
Xin Li +8 more
wiley +1 more source
Glycosylation in the tumor immune response: the bitter side of sweetness
Acta Biochimica et Biophysica SinicaGlycosylation is the most structurally diverse form of post-translational modification (PTM) of proteins that affects a myriad of cellular processes. As a pivotal regulator of protein homeostasis, glycosylation notably impacts the function of proteins ...
Cao Yuting, Yi Wen, Zhu Qiang
doaj +1 more source
Glycosylation of the surface glycoprotein of Halobacterium salinarium via a cyclic pathway of lipid‐linked intermediates [PDF]
, 1978 Matthew F. Mescher, Jack L. Strominger
openalex +1 more source
Advanced Science, EarlyView.The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao +11 more
wiley +1 more source
Advanced Science, EarlyView.Humanized milk fat globules (MFG) mimic the native composition and structure of human milk, achieved through remodeling of milk fat globule membrane phospholipid composition and reconstruction of the tri‐layer membrane structure. These humanized MFG exhibit improved structural stability and digestibility, and enhance neurodevelopment in formula‐fed rat
Shaolei Wang +8 more
wiley +1 more source
In silico evaluation of the role of Fab glycosylation in cetuximab antibody dynamics
Frontiers in ImmunologyIntroductionN-glycosylation is a post-translational modification that is highly important for the development of monoclonal antibodies (mAbs), as it regulates their biological activity, particularly in terms of immune effector functions.
Simona Saporiti +6 more
doaj +1 more source
Biocompatible Mesoporous Materials for Bone Therapy
Advanced Science, EarlyView.Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu +6 more
wiley +1 more source
Advanced Science, EarlyView.This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen +12 more
wiley +1 more source
Unveiling the metabolic fate of monosaccharides in cell membranes with glycomic and glycoproteomic analyses. [PDF]
, 2019 Cell membrane protein glycosylation is dependent on the metabolic state of the cell as well as exogenous nutrients available. Although the metabolism and interconversion of monosaccharides have been well-studied, their incorporation into cell surface ...
Cheng, Zhi +5 more
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