Results 141 to 150 of about 175,061 (321)
From glycosylation to glycosylation diseases
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2009 Gert Matthijs, Jacques Jaeken
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ChemBioChem, EarlyView.In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout +1 more
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Microbiology SpectrumAcross the Burkholderia genus O-linked protein glycosylation is highly conserved. While the inhibition of glycosylation has been shown to be detrimental for virulence in Burkholderia cepacia complex species, such as Burkholderia cenocepacia, little is ...
Jessica M. Lewis +4 more
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ChemBioChem, EarlyView.An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl +7 more
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Glycosylation of N6-benzyladenine by fusion procedure using bis-(p-nitrophenyl)hydrogen phosphate.
, 1976 Takeshi Hashizume, Kozo Yoshida
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Molecular Tweezers for Biomimetic Recognition of Carbohydrates
ChemBioChem, EarlyView.Molecular tweezers have emerged as effective binders for biomolecules such as lipids, nucleic acids, and proteins, eliciting biological activities. Tweezer molecules, which exploit an open and adaptive binding cavity, can target relatively large guests, such as oligosaccharides and glycans, and often provide some advantages over corresponding ...
Francesco Milanesi +3 more
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Glycosylation and rheumatic disease
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1998 Rheumatoid arthritis (RA) and other rheumatic diseases are associated with a significant defect in the galactosyltransferase enzyme that results in a profound change in the galactosylation of immunoglobulin G. This change has been demonstrated to be integrally associated with pathogenic mechanisms associated with inflammation in RA.
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Synthesis of α‐Arylglycosides by Ni‐Photoredox Arylation of Sugars with an Organic Photocatalyst
ChemCatChem, Accepted Article.Herein we report a Ni‐photoredox catalytic methodology for the synthesis of C‐aryl glycosides via arylation of monosaccharides unprotected at the anomeric position. In our work, the iridium‐complex previously employed as photocatalyst in this kind of Ni‐photoredox arylation of alcohols, was replaced by 5CzBN – a readily available donor‐acceptor ...
Gianluca Cavazzoli +6 more
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GlycanML: A Multi-Task and Multi-Structure Benchmark for Glycan Machine Learning [PDF]
arXivGlycans are basic biomolecules and perform essential functions within living organisms. The rapid increase of functional glycan data provides a good opportunity for machine learning solutions to glycan understanding. However, there still lacks a standard machine learning benchmark for glycan property and function prediction.
arxiv