Results 181 to 190 of about 406,798 (331)

The Mechanism and Potential Therapeutic Strategies of Vascular Aging

open access: yesAGING MEDICINE, EarlyView.
The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu   +4 more
wiley   +1 more source

In Situ NMR and Kinetics Reveal Origins of Regioselectivity Differences for Epichlorohydrin Ring‐Opening in Lewis and Brønsted Acid Zeolites

open access: yesAngewandte Chemie, EarlyView.
Regioselectivities for epichlorohydrin ring‐opening over Brønsted and Lewis acid zeolites change by an order of magnitude upon replacing fractions of methanol with acetonitrile co‐solvent. Combining transient operando 13C‐NMR with traditional kinetic measurements reveals that these differences originate from competition between an SN1 pathway through ...
David S. Potts   +5 more
wiley   +2 more sources

The Orthoester Glycosylation Method. Variations in the Anomeric Composition of the Product with Aglycone Basicity in the Two-Step Procedure. [PDF]

open access: bronze, 1976
Per J. Garegg   +5 more
openalex   +1 more source

Heat drastically alters floral color and pigment composition without affecting flower conspicuousness

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Floral pigments primarily serve to attract pollinators through color display and also contribute to protection against environmental stress. Although pigment composition can be plastically altered under stress, its impact on pollinator color perception remains poorly understood.
Eduardo Narbona   +6 more
wiley   +1 more source

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

STT3B promotes porcine epidemic diarrhea virus replication by regulating N-glycosylation of PEDV S protein

open access: yesJournal of Virology
Porcine epidemic diarrhea virus (PEDV), a highly pathogenic enteric coronavirus, has caused significant economic losses worldwide in recent years.
Huixin Zhu   +6 more
doaj   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio   +12 more
wiley   +1 more source

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