Results 181 to 190 of about 191,408 (290)

Investigation into biased signaling, glycosylation, and drug vulnerability of acute myeloid leukemia

Tomasz Pienkowski, Aleksandra Golonko, Łukasz Bołkuń, Katarzyna Wawrzak-Pienkowska, Łukasz Szczerbiński, Adam Krętowski, Michał Ciborowski, W. Lewandowski, Waldemar Priebe, Renata Świsłocka   +9 more
openalex   +1 more source

Exploring the Protein Glycosylation Pathways to Find New Therapeutic Alternatives

, 2015
Héctor M. Mora‐Montes
openalex   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source

Quantitative Modeling of IgG N-Glycosylation Profiles from Population Data. [PDF]

Int J Mol Sci
Kutumova E, Mandrik N, Sharipov R, Pučić-Baković M, Rapčan B, Aulchenko Y, Lauc G, Kolpakov F.   +7 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Proteomics Combined with N-Glycoproteomics to Explore the Pathogenesis of Nasopharyngeal Carcinoma. [PDF]

J Proteome Res
Chen X, Li Z, Ling H, Zhou Y, Wu Y, Lin Q.   +5 more
europepmc   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Intestinal Mucin Glycosylation: Structural Regulation, Homeostasis Maintenance and Disease Association. [PDF]

Biomolecules
Li Y, Pan J, Liu H, Liu C.
europepmc   +1 more source

Scale‐up of a monoclonal antibody CHO fed‐batch production in stirred tank bioreactors: Effect of hydrodynamic conditions and feeding regimen

Biotechnology Progress, EarlyView.
Abstract Key hydrodynamic‐related parameters such as volumetric power input (P/V), impeller configuration, aeration strategy, and maximum gas sparge rate, as well as an appropriate feeding strategy, must be carefully selected to improve production yields in bioreactor.
Lucas Lemire, Sebastian‐Juan Reyes, Yves Durocher, Robert Voyer, Olivier Henry, Phuong Lan Pham   +5 more
wiley   +1 more source

<i>SLC35A2</i>-Related Brain Disorders: Genetics, Pathophysiology, and Therapeutic Insights. [PDF]

Int J Mol Sci
Risso B, Riva A, Volpedo G, Conti V, di San Carlo CT, Zara F, Striano P, Falace A.   +7 more
europepmc   +1 more source