Results 211 to 220 of about 191,408 (290)

Novel Bioactive Multifunctional Polyphenols: A Chemo‐Enzymatic Approach

open access: yesChemistry – A European Journal, EarlyView.
One‐step synthesis of complex alkyl oxystilbenin glucosides (6‐47% yield) in alcoholic medium. Switching to ter‐BuOH as solvent afforded δ‐Viniferin diglucoside, with high selectivity and high yield (> 90%), that can be upgraded by enzymatic esterification to alkyl δ‐Viniferin diglucosides.
Amandine L. Flourat   +8 more
wiley   +1 more source

Anion-Assisted Glycosylation of Galactose: A Computational Study. [PDF]

open access: yesJ Org Chem
Tali K   +4 more
europepmc   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius   +6 more
wiley   +1 more source

Fluorescent Dyes for Probing Intracellular and Subcellular Polarity

open access: yesChemistry–Methods, EarlyView.
Fluorescent probes are crucial tools for measuring cellular microenvironment polarity, a parameter that influences physiological organelle function and diseases such as cancer. This text details the probes' physicochemical principles, intracellular targeting strategies, and key photophysical parameters for polarity estimation.
M. Carmen Gonzalez‐Garcia   +4 more
wiley   +1 more source

The Formation of Covalent Linkages in Lignocellulosic Biomass via the Oxocarbenium Intermediate

open access: yesChemPhysChem, EarlyView.
Density functional theory models show that the hydrated and acidic hemicellulose matrix in lignocellulosic biomass can generate oxocarbenium ions. These reactive intermediates can participate in the stable formation of glycosidic lignin‐carbohydrate covalent linkages, promoting recalcitrance in plant biomass.
Eduardo Romero‐Montalvo   +1 more
wiley   +1 more source

Capability Development in the European Medicines Regulatory Network—A European Learning Needs Analysis and Survey Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The European Medicines Regulatory Network plays a critical role in safeguarding public health through the assessment and supervision of human medicines. However, rapid scientific and technological advancements have exposed capability deficits across the network, threatening timely and effective regulatory decision‐making.
Naomi Beard   +4 more
wiley   +1 more source

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