Results 171 to 180 of about 136,588 (299)

Genome-Wide Identification of the Glycosyltransferase 4 Family and Characterization of <i>GmSPS8</i> Associated with Seed Weight in Soybean. [PDF]

Curr Issues Mol Biol
Cao H, Liu L, Zhang K, Ma S, Wang M, Sun Y, Zhuang Y, Chen B, Zhang J, Zhang D, Li X.   +10 more
europepmc   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, Volume 13, Issue 51, 14 September 2026.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Establishing "Glycoantigens" as a cross-field concept in Glycobiology, transfusion, transplant, and immunology. [PDF]

Hum Immunol
Lane WJ.
europepmc   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, Volume 13, Issue 54, 28 September 2026.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Gut microbiota functional remodeling and butyrate depletion amplify anti-Ro/La antibody-driven type I interferon activation in neonatal lupus. [PDF]

Gut Microbes
Sun W, Li Y, Liu X, Yu S, Li W, Wang H, Geng H, Li L, Hu J, Huo J, Zhang W, Fu J, Jin X, Li H, Zhou X, Zhu X.   +15 more
europepmc   +1 more source

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2010-2018, September 2026.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillmann, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano   +25 more
wiley   +1 more source

Functional and mechanistic characterization of the phosphatidyl-<i>myo</i>-inositol mannosyltransferase PimA from <i>Mycobacterium tuberculosis</i>: implications for anti-tuberculosis drug development. [PDF]

Front Cell Infect Microbiol
Liu D, Deng H, Liu X, Yao W, Li N.
europepmc   +1 more source

CMS4 epithelial-intrinsic glycosyltransferase GALNT5 promotes tumor aggressiveness and correlates with poor survival in colorectal cancer. [PDF]

Sci Rep
Hayashishita S, Okayama H, Nakajima S, Saito K, Takiguchi C, Mitsui D, Matsuida H, Katagata M, Sato T, Matsumoto T, Ujiie D, Chida S, Saze Z, Saito M, Mimura K, Momma T, Kono K.   +16 more
europepmc   +1 more source

Crystal structure of a β1,3-Glucosyltransferase reveals an unusual substrate recognition by a two-domain GT-A fold glycosyltransferase. [PDF]

J Biol Chem
Berardinelli SJ, Kadirvelraj R, Luther KB, Gao Z, Chapla D, Huang C, Tehrani DM, Zhang A, Moremen KW, Wood ZA, Haltiwanger RS.   +10 more
europepmc   +1 more source

POFUT1 Serves as an Independent Prognostic Factor and Therapeutic Target by Activating the PI3K/AKT Pathway in Glioma

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective Protein O‐fucosyltransferase 1 (POFUT1) has been implicated in several malignancies, but its functional and prognostic significance in glioma remains insufficiently defined. This study evaluated whether POFUT1 expression is associated with glioma progression, patient outcome, and PI3K/AKT pathway activity.
Kai Yang, Chunlei Ju, Yifan Wang, Aijie Guo, Xiaochen Yang, Yang Mi, Yifei Su, Chunhong Wang, Hongming Ji   +8 more
wiley   +1 more source