Fitness costs of phage-driven resistance mutations in <i>Salmonella</i> Enteritidis populations. [PDF]
Lv P +8 more
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Evolving threats: Leveraging C. elegans to decode the virulence profiles of highly related environmental Salmonella Newport isolates. [PDF]
Ferreira CM +7 more
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Multiplex CRISPR/Cas9-mediated editing of seven glycosyltransferase homologs in <i>Nicotiana benthamiana</i> to produce stable, Cas9-free, glycoengineered plants. [PDF]
Kaur C +9 more
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Efficient whole-cell biotransformation for gastrodin production via glycosyltransferase engineering and process optimization. [PDF]
Wang X +5 more
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N-Glycoengineering of insect cells for tri-antennary N-glycan biosynthesis. [PDF]
Kajiura H +5 more
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SEDS glycosyltransferases in <i>E. faecalis</i> are upregulated by the CroS/R two-component system to enhance peptidoglycan synthesis during cell wall stress. [PDF]
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Glycosyltransferases and their Assays
ChemBioChem, 2010AbstractGlycosyltransferases (GTs) are a large family of enzymes that are essential in all domains of life for the biosynthesis of complex carbohydrates and glycoconjugates. GTs catalyse the transfer of a sugar from a glycosyl donor to a variety of acceptor molecules, for example, oligosaccharides, peptides, lipids or small molecules.
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Glycosyltransferases are involved in the biosyntheses of cell-wall polysaccharides, the addition of N-linked glycans to glycoproteins, and the attachment of sugar moieties to various small molecules such as hormones and flavonoids. In the past two years, substantial progress has been made in the identification and cloning of genes that encode ...
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Antibiotic glycosyltransferases
Biochemical Society Transactions, 2003In the biosynthesis of several classes of antibiotics, sugars are attached to aglycone scaffolds by antibiotic-specific glycosyltransferases in the latter stages of the pathways. Two glycosylation pathways will be examined: the glycopeptide antibiotics of the vancomycin class and the aminocoumarin antibiotics of the novobiocin class.
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