Results 191 to 200 of about 126,630 (231)
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The conformational plasticity of glycosyltransferases
Current Opinion in Structural Biology, 2016Glycosyltransferases (GTs) catalyze the transfer of a sugar moiety from nucleotide-sugar or lipid-phospho-sugar donors to a broad range of acceptor substrates, generating a significant amount of structural diversity in biological systems. GTs are highly selective in nature, allowing the recognition of subtle structural differences in the sequences and ...
David Albesa-Jové, Marcelo E Guerin
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Photoaffinity labelling of glycosyltransferases
Glycobiology, 1992The photoaffinity analogues 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid have proven to be valuable biochemical tools in the studies of nucleoside diphosphate sugar-utilizing enzymes, especially membrane-associated glycosyltransferases. A summary of the past and current uses of these analogues is presented, as well as photoaffinity data for the ...
R R, Drake, A D, Elbein
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Glycosyltransferases in SWISS-PROT
Glycoconjugate Journal, 1998SWISS-PROT is a curated protein sequence database with a high level of annotation (such as description of the function of a protein, its domain structure, post-translational modification, variants, etc), a minimal level of redundancy and a high level of integration with other databases.
C, O'Donovan, N, Mitaritonna
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Glycosyltransferases, glycosylation and atherosclerosis
Glycoconjugate Journal, 2014Cardiovascular diseases arising from atherosclerosis are currently the leading cause of mortality worldwide. Leukocyte recruitment is a key step for the successful initiation of atherosclerosis and occurs predominantly in the inflamed endothelium. Leukocyte recruitment is mediated by a group of adhesive molecules and chemokine receptors, which are ...
Qianghong, Pu, Chao, Yu
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Mechanisms of Glycosyltransferases: The In and the Out
ChemBioChem, 2011Getting into a transition state: Glycosyltransferases retain a critical role in glycobiology. The design of potent glycosyltransferase inhibitors may be facilitated by considering the mechanistic evidence presented by Davies and Davis and co-workers that strengthens the case that retaining glycosyltransferases function through a single front-side, S(N ...
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GLYCOSYLTRANSFERASES OF LIPOPHILIC SMALL MOLECULES
Annual Review of Plant Biology, 2006Glycosyltransferases of small molecules transfer sugars to a wide range of acceptors, from hormones and secondary metabolites to biotic and abiotic chemicals and toxins in the environment. The enzymes are encoded by large multigene families and can be identified by a signature motif in their primary sequence, which classifies them as a subset of ...
Bowles, Dianna J +3 more
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Activity Determination of Glycosyltransferases
2019The unique chemistry of 2-aminobenzoic acid (2-AA, anthranilic acid, AA) for labeling glycans in aqueous buffer solutions was crucial in developing the assays for measuring the activity of transferases (Anumula, Anal Biochem 457:31-37, 2014).
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Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis
International Journal of Biological Macromolecules, 2021Chang Zhao, Yunzi Luo, Rui Bao
exaly
MALDI Imaging Assisted Discovery of a Di‐O‐glycosyltransferase from Platycodon grandiflorum Root
Angewandte Chemie - International Edition, 2023Xu Lu, Bin Li
exaly