Novel <i>ALG13</i> Variants and an Expanded Neurodevelopmental Spectrum: Genotype-Phenotype Correlations. [PDF]
Su S +5 more
europepmc +1 more source
Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss +12 more
wiley +1 more source
Identification of a novel ABO*A1.01 allele with c.562C>T (p.Arg188Cys) mutation associated with A<sub>el</sub> phenotype in a Chinese individual. [PDF]
Xu X +5 more
europepmc +1 more source
Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao +10 more
wiley +1 more source
LIPE‐AS1 is markedly upregulated and serves as a competitive endogenous RNA that sponges miR‐330‐3p. This sequestration relieves miR‐330‐3p‐mediated repression of MGAT5, leading to elevated MGAT5, which subsequently suppresses cuproptosis‐related proteins FDX1, DLAT, and DLST, thus diminishing cuproptosis sensitivity.
Qiang Shen +18 more
wiley +1 more source
ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan +3 more
wiley +1 more source
Isolation and characterization of <i>Novosphingobium oxfordense</i> sp. nov. and <i>Novosphingobium mississippiense</i> sp. nov. from soil, with LC-MS/MS and genome-based investigation of their glycosphingolipid production. [PDF]
Ali T, Boudreau PD.
europepmc +1 more source
Tomato yellow leaf curl virus upregulates the Bemisia tabaci UDP‐glycosyltransferase gene UDP‐Bta06664. RNA interference (RNAi) silencing of this gene disrupts phloem feeding—delaying E1 and shortening E2—and reduces both virus acquisition and inoculation, highlighting its potential as an RNAi target.
Zeyu Wan +5 more
wiley +1 more source
PgUGT84K2, a Panax ginseng glycosyltransferase, catalyses IBA glycosylation and enhances abiotic stress tolerance in transgenic Arabidopsis. [PDF]
Chang F +6 more
europepmc +1 more source
Uptake, metabolism, and bioremediation of neonicotinoid insecticides in soil–plant systems: A review
This review summarizes the uptake and metabolic transformation of neonicotinoid insecticides in plants, showing that some metabolites exhibit higher toxicity. We also critically assess promising bioremediation strategies using microbes and plant–microbe interactions to reduce residue contamination.
Wenwen Guo +5 more
wiley +1 more source

