Results 191 to 200 of about 136,588 (299)

Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss   +12 more
wiley   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao   +10 more
wiley   +1 more source

LIPE‐AS1 Facilitates Prostate Cancer Progression via Suppressing Cuproptosis Through the miR‐330‐3p/MGAT5 Axis

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
LIPE‐AS1 is markedly upregulated and serves as a competitive endogenous RNA that sponges miR‐330‐3p. This sequestration relieves miR‐330‐3p‐mediated repression of MGAT5, leading to elevated MGAT5, which subsequently suppresses cuproptosis‐related proteins FDX1, DLAT, and DLST, thus diminishing cuproptosis sensitivity.
Qiang Shen   +18 more
wiley   +1 more source

Heparan sulfate and glycomimetics: Advances in synthesis and biological applications for post‐stroke neurorepair

open access: yesNeuroprotection, Volume 4, Issue 3, Page 213-228, September 2026.
ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan   +3 more
wiley   +1 more source

Targeting UDP‐Bta06664 in Bemisia tabaci: A novel strategy to reduce tomato yellow leaf curl virus transmission by impairing insect vector feeding

open access: yesNew Plant Protection, Volume 3, Issue 3, September 2026.
Tomato yellow leaf curl virus upregulates the Bemisia tabaci UDP‐glycosyltransferase gene UDP‐Bta06664. RNA interference (RNAi) silencing of this gene disrupts phloem feeding—delaying E1 and shortening E2—and reduces both virus acquisition and inoculation, highlighting its potential as an RNAi target.
Zeyu Wan   +5 more
wiley   +1 more source

Uptake, metabolism, and bioremediation of neonicotinoid insecticides in soil–plant systems: A review

open access: yesNew Plant Protection, Volume 3, Issue 3, September 2026.
This review summarizes the uptake and metabolic transformation of neonicotinoid insecticides in plants, showing that some metabolites exhibit higher toxicity. We also critically assess promising bioremediation strategies using microbes and plant–microbe interactions to reduce residue contamination.
Wenwen Guo   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy