Identification and Characterization of a Putative Kaempferol Glucosyltransferase UGT78G3 in <i>Medicago truncatula</i>. [PDF]
Yin P +8 more
europepmc +1 more source
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou +6 more
wiley +1 more source
Letter to the Editor Regarding "EXT2 promotes sarcoma progression and immune evasion via the AKT/c-Myc/PD-L1 axis: a multi-omics and validation study". [PDF]
Song Q, Liu Y, Dou F.
europepmc +1 more source
RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run +7 more
wiley +1 more source
Genetic control of Group 3 (K96) capsule synthesis and complement resistance in extraintestinal pathogenic <i>Escherichia coli</i>. [PDF]
David Prince RJ +8 more
europepmc +1 more source
Donor‐induced conformational gating and substrate‐assisted catalysis in α‐1,3‐galactosyltransferase
Abstract Retaining glycosyltransferases catalyze the formation of stereochemically conserved glycosidic bonds through mechanisms that remain debated. Using bovine α1,3‐galactosyltransferase (α3GalT) as a model, we combine mutagenesis, equilibrium unfolding, kinetics, and molecular dynamics simulations to understand how donor‐induced loop ordering ...
Javier A. Linares‐Pastén +1 more
wiley +1 more source
Elucidation of the Pathway for the Biosynthesis of the Undecorated Capsular Polysaccharide from the HS:19 Serotype of the Human Pathogen <i>Campylobacter jejuni</i>. [PDF]
Xiang DF, Narindoshvili T, Raushel FM.
europepmc +1 more source
Abstract Barley (Hordeum vulgare L.) is an important crop in the world, and its seed dormancy is primarily controlled by a mitogen‐activated protein kinase kinase 3 (MKK3) gene. Although kinase activity of MKK3 and its roles in barley post‐domestication have been widely studied, the pre‐domestication evolution of MKK3 and the spread of nondormant ...
Lydia G. Tressel +3 more
wiley +1 more source
Exploring the genetic architecture underlying dietary fiber content in Colombian Andean blueberry (Vaccinium meridionale Swartz). [PDF]
Anacona GPV +4 more
europepmc +1 more source

