Results 201 to 210 of about 136,588 (299)

Impact of the GouM transporter on secondary metabolism activation and production yield in Streptomyces noursei strain CK‐15

open access: yesNew Plant Protection, Volume 3, Issue 3, September 2026.
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou   +6 more
wiley   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

open access: yesPrecision Medical Sciences, Volume 15, Issue 3, Page 176-193, September 2026.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run   +7 more
wiley   +1 more source

Genetic control of Group 3 (K96) capsule synthesis and complement resistance in extraintestinal pathogenic <i>Escherichia coli</i>. [PDF]

open access: yesmSphere
David Prince RJ   +8 more
europepmc   +1 more source

Donor‐induced conformational gating and substrate‐assisted catalysis in α‐1,3‐galactosyltransferase

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Retaining glycosyltransferases catalyze the formation of stereochemically conserved glycosidic bonds through mechanisms that remain debated. Using bovine α1,3‐galactosyltransferase (α3GalT) as a model, we combine mutagenesis, equilibrium unfolding, kinetics, and molecular dynamics simulations to understand how donor‐induced loop ordering ...
Javier A. Linares‐Pastén   +1 more
wiley   +1 more source

Genomic and evolutionary analysis reveals dynamic variations of MKK3 gene, a key regulator for seed dormancy in barley

open access: yesThe Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Barley (Hordeum vulgare L.) is an important crop in the world, and its seed dormancy is primarily controlled by a mitogen‐activated protein kinase kinase 3 (MKK3) gene. Although kinase activity of MKK3 and its roles in barley post‐domestication have been widely studied, the pre‐domestication evolution of MKK3 and the spread of nondormant ...
Lydia G. Tressel   +3 more
wiley   +1 more source

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