Results 181 to 190 of about 126,630 (231)

Glycoconjugate glycosyltransferases

Glycoconjugate Journal, 2008
Assay methods for representative glycosyltransferases were described, covering those involved in the synthesis of glycosphingolipids, N-glycans, O-glycans, and proteoglycan glycosaminoglycans. In addition, intracellular localization of glycosyltransferase was comprehensively summarized.
Koichi, Furukawa, Akiko, Tsuchida, Tetsuya, Okajima, Keiko, Furukawa   +3 more
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GLYCOSYLTRANSFERASES IN OLIGOSACCHARIDE SYNTHESIS

Journal of Carbohydrate Chemistry, 2001
AbstractFor Abstract see ChemInform Abstract in Full Text.
Xiangping Qiam, Keiko Sujino, Monica M. Palcic, R. Murray Ratcliffe   +3 more
openaire   +1 more source

Iminosugars as glycosyltransferase inhibitors

Organic & Biomolecular Chemistry, 2021
The review describes the syntheses and inhibition properties of pyrrolidine, piperidine, azepane, pyrrolizidine and indolizidine iminosugars, as well as iminosugar nucleotides and iminodi- and -oligosaccharides.
Irene Conforti, Alberto Marra
openaire   +2 more sources

Glycosyltransferases as biocatalysts

Current Opinion in Chemical Biology, 2011
Glycosyltransferases are useful synthetic tools for the preparation of natural oligosaccharides, glycoconjugates and their analogues. High expression levels of recombinant enzymes have allowed their use in multi-step reactions, on mg to multi-gram scales.
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Comparative aspects of glycosyltransferases

Biochemical Society Symposia, 2002
Glycosyltransferases, the enzymes that build oligosaccharides and glycoconjugates, have received much interest in recent years owing to their biological functions and their potential uses in biotechnology. Despite the fact that many glycosyltransferases recognize similar donor or acceptor substrates, there is surprisingly limited sequence identity ...
Breton, C., Heissigerova, H., Jeanneau, C., Moravcova, J., Imberty, A.   +4 more
openaire   +2 more sources

Glycosyltransferase structure and mechanism

Current Opinion in Structural Biology, 2000
The high-resolution X-ray crystal structures of a new form of bacteriophage T4 beta-glucosyltransferase, Escherichia coli MurG, Bacillus subtilis SpsA, bovine beta-1,4-galactosyltransferase 1 and rabbit N-acetylglucosaminyltransferase I have now been solved.
U M, Unligil, J M, Rini
openaire   +2 more sources

Exploring genomes for glycosyltransferases

Molecular BioSystems, 2010
Abstract Glycosyltransferases are one of the largest and most diverse enzymegroups in Nature. They catalyse the synthesis of glycosidic linkages by the transfer of a sugar residue from a donor to an acceptor substrate. These enzymes have been classified into families on the basis of amino acid sequence similarity that are kept updated
Fasmer Hansen, Sara, Bettler, Emmanuel, Rinnan, Åsmund, Engelsen, Søren Balling, Breton, Christelle   +4 more
openaire   +3 more sources

Engineering of glycosidases and glycosyltransferases

Current Opinion in Chemical Biology, 2006
In recent years, substantial advances have been made in the engineering of glycosidases and glycosyltransferases for the synthesis and degradation of glycan structures. Key developments include improvement of the thermostability of xylanase through comprehensive saturation mutagenesis, creation of the first glycosynthase derived from an inverting ...
Susan M, Hancock, Mark D, Vaughan, Stephen G, Withers   +2 more
openaire   +2 more sources

Molecular Modeling of Glycosyltransferases

2006
Glycosyltransferases, the enzymes that build oligosaccharides and glycoconjugates, have received much interest in recent years owing to their biological functions and their potential uses in biotechnology. The analysis of the wealth of sequences that are now available in databases allowed the classification in different families characterized by ...
Imberty, A., Wimmerova, M., Koca, J., Breton, C.   +3 more
openaire   +2 more sources

Affinity chromatography of glycosyltransferases

Journal of Chromatography A, 1981
This review summarizes the use of biospecific chromatography techniques in the purification of mammalian glycosyltransferases. Ligands that are analogues of donor or acceptor substrates have been linked to cyanogen bromide-activated agarose for use as affinity adsorbents.
J E, Sadler, T A, Beyer, R L, Hill
openaire   +2 more sources