Results 211 to 220 of about 150,012 (247)
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Iminosugars as glycosyltransferase inhibitors
Organic & Biomolecular Chemistry, 2021The review describes the syntheses and inhibition properties of pyrrolidine, piperidine, azepane, pyrrolizidine and indolizidine iminosugars, as well as iminosugar nucleotides and iminodi- and -oligosaccharides.
Irene Conforti, Alberto Marra
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GLYCOSYLTRANSFERASES IN OLIGOSACCHARIDE SYNTHESIS
Journal of Carbohydrate Chemistry, 2001AbstractFor Abstract see ChemInform Abstract in Full Text.
Xiangping Qiam +3 more
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Glycosyltransferases as biocatalysts
Current Opinion in Chemical Biology, 2011Glycosyltransferases are useful synthetic tools for the preparation of natural oligosaccharides, glycoconjugates and their analogues. High expression levels of recombinant enzymes have allowed their use in multi-step reactions, on mg to multi-gram scales.
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Glycosyltransferase structure and mechanism
Current Opinion in Structural Biology, 2000The high-resolution X-ray crystal structures of a new form of bacteriophage T4 beta-glucosyltransferase, Escherichia coli MurG, Bacillus subtilis SpsA, bovine beta-1,4-galactosyltransferase 1 and rabbit N-acetylglucosaminyltransferase I have now been solved.
U M, Unligil, J M, Rini
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2015
AbstractThe stereo- and regioselective properties and the high selectivity of glycosyltransferases toward donor and acceptor substrates make these enzymes highly attractive for synthetic applications. Various examples of recombinantly expressed glycosyltransferases demonstrate the versatility of both in vivo and in vitro syntheses of oligosaccharides ...
J. Voglmeir, S. L. Flitsch
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AbstractThe stereo- and regioselective properties and the high selectivity of glycosyltransferases toward donor and acceptor substrates make these enzymes highly attractive for synthetic applications. Various examples of recombinantly expressed glycosyltransferases demonstrate the versatility of both in vivo and in vitro syntheses of oligosaccharides ...
J. Voglmeir, S. L. Flitsch
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Exploring genomes for glycosyltransferases
Molecular BioSystems, 2010Glycosyltransferases are one of the largest and most diverse enzyme groups in Nature. They catalyse the synthesis of glycosidic linkages by the transfer of a sugar residue from a donor to an acceptor substrate. These enzymes have been classified into families on the basis of amino acid sequence similarity that are kept updated in the Carbohydrate ...
Fasmer Hansen, Sara +4 more
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Glycosyltransferases and their Assays
ChemBioChem, 2010AbstractGlycosyltransferases (GTs) are a large family of enzymes that are essential in all domains of life for the biosynthesis of complex carbohydrates and glycoconjugates. GTs catalyse the transfer of a sugar from a glycosyl donor to a variety of acceptor molecules, for example, oligosaccharides, peptides, lipids or small molecules.
Wagner, GK, Pesnot, T
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Molecular Modeling of Glycosyltransferases
2006Glycosyltransferases, the enzymes that build oligosaccharides and glycoconjugates, have received much interest in recent years owing to their biological functions and their potential uses in biotechnology. The analysis of the wealth of sequences that are now available in databases allowed the classification in different families characterized by ...
Imberty, A. +3 more
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Cell Surface Glycosyltransferase Activities
1980Publisher Summary Three basic components are involved in the reactions catalyzed by glycosyltransferases. These are the enzyme itself, a sugar donor, and a sugar acceptor. Often divalent cations are needed for catalytic activity. Another component, α-lactalbumin also participates in the reactions of some galactosyltransferases.
M, Pierce, E A, Turley, S, Roth
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