Results 171 to 180 of about 42,851 (291)
A cell-permeable probe for the labelling of a bacterial glycosyltransferase and virulence factor
Yong Xu, Gerd K. Wagner
openalex +2 more sources
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio +12 more
wiley +1 more source
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley +1 more source
Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine ...
M V N L Chaitanya +14 more
wiley +1 more source
Metatranscriptomic analysis of Centaurea cyanus revealed diverse plant‐associated viral and bacterial sequences in herbicide‐susceptible and ‐resistant biotypes. While novel partitiviruses occurred independently of resistance status, differences in bacterial community composition may suggest a potential role of the plant microbiome in responses to ...
Katarzyna Marcinkowska +2 more
wiley +1 more source
A neural glycan HNK-1 is transferred to recipient cells via small extracellular vesicles. [PDF]
Tokoro Y, Kizuka Y.
europepmc +1 more source
Estrone‐α‐2DG, synthesized via a one‐pot multi‐enzyme system, selectively inhibits aromatase (IC50 = 0.101μM) and triple negative breast cancer cells (IC50 = 20.46 μM), offering a dual function therapeutic scaffold. ABSTRACT Aromatase inhibitors (AIs) are vital in the treatment of estrogen‐dependent breast cancer, especially in postmenopausal women. In
Tzu‐Yu Huang +5 more
wiley +1 more source
Sugar for the trip: Pollen tube development requires glycosylated flavonols. [PDF]
Flores-Tornero M.
europepmc +1 more source
Advances and challenges in plant N-glycoengineering: when fucosylation matters. [PDF]
Gauba K, Kunnummel V, Castilho A.
europepmc +1 more source

