Results 41 to 50 of about 22,975 (220)

Towards inhibitors of glycosyltransferases: A novel approach to the synthesis of 3-acetamido-3-deoxy-D-psicofuranose derivatives

Beilstein Journal of Organic Chemistry, 2015
A novel synthetic strategy leading to 3-acetamido-3-deoxy-D-psicofuranose 9 is presented. The latter compound, after some manipulations, was transformed into fully protected 3-acetamido-3-deoxy-D-psicofuranose 11 as a potential substrate for the ...
Maroš Bella, Miroslav Koóš, Chun-Hung Lin   +2 more
doaj   +1 more source

Crossroads between bacterial and mammalian glycosyltransferases

Frontiers in Immunology, 2014
Bacterial glycosyltransferases often synthesize the same glycan linkages as mammalian glycosyltransferases, yet they usually have very little sequence identity.
Inka eBrockhausen
doaj   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Cell Wall Enzymes in Zygnema circumcarinatum UTEX 1559 Respond to Osmotic Stress in a Plant-Like Fashion

Frontiers in Plant Science, 2019
Previous analysis of charophyte green algal (CGA) genomes and transcriptomes for specific protein families revealed that numerous land plant characteristics had already evolved in CGA.
Elisabeth Fitzek, Elisabeth Fitzek, Elisabeth Fitzek, Lauren Orton, Sarah Entwistle, W. Scott Grayburn, Catherine Ausland, Melvin R. Duvall, Yanbin Yin, Yanbin Yin   +9 more
doaj   +1 more source

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside

Advanced Science, EarlyView.
This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu, Shan Zhang, Shanrong Wei, Ziye Xing, Hongming He, Xiao Liang, Quanshun Li   +6 more
wiley   +1 more source

Secoisolariciresinol Diglucoside of Flaxseed and Its Metabolites: Biosynthesis and Potential for Nutraceuticals

Frontiers in Genetics, 2018
Secoisolariciresinol diglucoside (SDG), found mainly in flaxseed, is one of the essential lignans. SDG, as well as the beneficial fatty acid composition and high fiber content, has made flaxseed an important source of functional food or nutraceutical ...
Parfait Kezimana, Parfait Kezimana, Alexey A. Dmitriev, Anna V. Kudryavtseva, Elena V. Romanova, Nataliya V. Melnikova   +5 more
doaj   +1 more source

Glycoside Hydrolases and Glycosyltransferases from Hyperthermophilic Archaea: Insights on Their Characteristics and Applications in Biotechnology

Biomolecules, 2021
Hyperthermophilic Archaea colonizing unnatural habitats of extremes conditions such as volcanoes and deep-sea hydrothermal vents represent an unmeasurable bioresource for enzymes used in various industrial applications.
Khadija Amin, Sylvain Tranchimand, Thierry Benvegnu, Ziad Abdel-Razzak, Hala Chamieh   +4 more
doaj   +1 more source

Expression cloning of glycosyltransferases [PDF]

Glycobiology, 1996
Cloning of cDNAs encoding glycosyltransferases enters into a new era because of the advent of expression cloning for glycosyltransferases. This mini-review summarizes a short historical view on the development of this method and surveys various improvements over the original method. This review also emphasizes the advantages of those recently developed
M, Fukuda, M F, Bierhuizen, J, Nakayama
openaire   +2 more sources

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

N-glycomic Complexity in Anatomical Simplicity: Caenorhabditis elegans as a Non-model Nematode?

Frontiers in Molecular Biosciences, 2019
Caenorhabditis elegans is a genetically well-studied model nematode or “worm”; however, its N-glycomic complexity is actually baffling and still not completely unraveled. Some features of its N-glycans are, to date, unique and include bisecting galactose
Katharina Paschinger, Shi Yan, Iain B. H. Wilson   +2 more
doaj   +1 more source