Results 21 to 30 of about 26,147 (300)
The yeast expression system for recombinant glycosyltransferases [PDF]
, 1999 Glycosyltransferases are increasingly being used for in vitro synthesis of oligosaccharides. Since these enzymes are difficult to purify from natural sources, expression systems for soluble forms of the recombinant enzymes have been developed.
Malissard, Martine +2 more
core +1 more source
Mucin-Type O-Glycosylation in Gastric Carcinogenesis
Biomolecules, 2016 Mucin-type O-glycosylation plays a crucial role in several physiological and pathological processes of the gastric tissue. Modifications in enzymes responsible for key glycosylation steps and the consequent abnormal biosynthesis and expression of their ...
Henrique O. Duarte +5 more
doaj +1 more source
Processivity in Bacterial Glycosyltransferases [PDF]
ACS Chemical Biology, 2019 Extracellular polysaccharides and glycoproteins of pathogenic bacteria assist in adherence, autoaggregation, biofilm formation, and host immune system evasion. As a result, considerable research in the field of glycobiology is dedicated to study the composition and function of glycans associated with virulence, as well as the enzymes involved in their ...
Liubov Yakovlieva, Marthe T. C. Walvoort
openaire +3 more sources
Frontiers in Oncology, 2021 Heparan Sulfate Proteoglycans (HSPGs) are important cell surface and Extracellular Matrix (ECM) maestros involved in the orchestration of multiple cellular events in physiology and pathology.
Catarina Marques +10 more
doaj +1 more source
IUCrJ, 2021 Lipid II, the main component of the bacterial cell wall, is synthesized by the addition of UDP-N-acetylglucosamine to the UDP-N-acetylmuramic acid pentapeptide catalyzed by the glycosyltransferase MurG.
Kyoung Ho Jung +4 more
doaj +1 more source
The Suitability of Orthogonal Hosts to Study Plant Cell Wall Biosynthesis
Plants, 2019 Plant cells are surrounded by an extracellular matrix that consists mainly of polysaccharides. Many molecular components involved in plant cell wall polymer synthesis have been identified, but it remains largely unknown how these molecular players ...
Markus Pauly +6 more
doaj +1 more source
Frontiers in Microbiology, 2021 Polar flagella from mesophilic Aeromonas strains have previously been shown to be modified with a range of glycans. Mass spectrometry studies of purified polar flagellins suggested the glycan typically includes a putative pseudaminic acid like derivative;
Gabriel Forn-Cuní +8 more
doaj +1 more source
The Role of Glycosyltransferases in Colorectal Cancer [PDF]
International Journal of Molecular Sciences, 2021 Colorectal cancer (CRC) is one of the main causes of cancer death in the world. Post-translational modifications (PTMs) have been extensively studied in malignancies due to its relevance in tumor pathogenesis and therapy. This review is focused on the dysregulation of glycosyltransferase expression in CRC and its impact in cell function and in several ...
Cecilia Fernández-Ponce +9 more
openaire +5 more sources
Foods, 2023 Leuconostoc mesenteroides strains are common contributors in fermented foods producing a wide variety of polysaccharides from sucrose through glycosyltransferases (GTFs).
Luz Cristina Vallejo-García +3 more
doaj +1 more source
Open Biology, 2021 The dystroglycan (DG) complex plays a pivotal role for the stabilization of muscles in Metazoa. It is formed by two subunits, extracellular α-DG and transmembrane β-DG, originating from a unique precursor via a complex post-translational maturation ...
Maria Giulia Bigotti, Andrea Brancaccio
doaj +1 more source