Results 21 to 30 of about 38,132 (292)

Trapping and Characterization of the Reaction Intermediate in Cyclodextrin Glycosyltransferase by Use of Activated Substrates and a Mutant Enzyme [PDF]

open access: yes, 1997
Cyclodextrin glycosyltransferases (CGTases) catalyze the degradation of starch into linear or cyclic oligosaccharides via a glycosyl transfer reaction occurring with retention of anomeric configuration.
Dijkstra, Bauke W.,   +4 more
core   +3 more sources

Mucin-Type O-Glycosylation in Gastric Carcinogenesis

open access: yesBiomolecules, 2016
Mucin-type O-glycosylation plays a crucial role in several physiological and pathological processes of the gastric tissue. Modifications in enzymes responsible for key glycosylation steps and the consequent abnormal biosynthesis and expression of their ...
Henrique O. Duarte   +5 more
doaj   +1 more source

Heparan Sulfate Biosynthesis and Sulfation Profiles as Modulators of Cancer Signalling and Progression

open access: yesFrontiers in Oncology, 2021
Heparan Sulfate Proteoglycans (HSPGs) are important cell surface and Extracellular Matrix (ECM) maestros involved in the orchestration of multiple cellular events in physiology and pathology.
Catarina Marques   +10 more
doaj   +1 more source

Biosynthesis of mycobacterial arabinogalactan: identification of a novel (13)arabinofuranosyltransferase [PDF]

open access: yes, 2008
The cell wall mycolyl-arabinogalactan-peptidoglycan complex is essential in mycobacterial species, such as Mycobacterium tuberculosis and is the target of several anti-tubercular drugs.
Alderwick, Luke J.   +9 more
core   +1 more source

Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG

open access: yesIUCrJ, 2021
Lipid II, the main component of the bacterial cell wall, is synthesized by the addition of UDP-N-acetylglucosamine to the UDP-N-acetylmuramic acid pentapeptide catalyzed by the glycosyltransferase MurG.
Kyoung Ho Jung   +4 more
doaj   +1 more source

Processivity in Bacterial Glycosyltransferases [PDF]

open access: yesACS Chemical Biology, 2019
Extracellular polysaccharides and glycoproteins of pathogenic bacteria assist in adherence, autoaggregation, biofilm formation, and host immune system evasion. As a result, considerable research in the field of glycobiology is dedicated to study the composition and function of glycans associated with virulence, as well as the enzymes involved in their ...
Liubov Yakovlieva, Marthe T. C. Walvoort
openaire   +3 more sources

Polar Flagella Glycosylation in Aeromonas: Genomic Characterization and Involvement of a Specific Glycosyltransferase (Fgi-1) in Heterogeneous Flagella Glycosylation

open access: yesFrontiers in Microbiology, 2021
Polar flagella from mesophilic Aeromonas strains have previously been shown to be modified with a range of glycans. Mass spectrometry studies of purified polar flagellins suggested the glycan typically includes a putative pseudaminic acid like derivative;
Gabriel Forn-Cuní   +8 more
doaj   +1 more source

Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells [PDF]

open access: yes, 2015
Protein O-glycosylation has key roles in many biological processes, but the repertoire of O-glycans synthesized by cells is difficult to determine. Here we describe an approach termed Cellular O-Glycome Reporter/Amplification (CORA), a sensitive method ...
Antonopoulos, A   +9 more
core   +1 more source

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]

open access: yes, 2020
Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp   +11 more
core   +2 more sources

The Suitability of Orthogonal Hosts to Study Plant Cell Wall Biosynthesis

open access: yesPlants, 2019
Plant cells are surrounded by an extracellular matrix that consists mainly of polysaccharides. Many molecular components involved in plant cell wall polymer synthesis have been identified, but it remains largely unknown how these molecular players ...
Markus Pauly   +6 more
doaj   +1 more source

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