Results 11 to 20 of about 26,147 (300)

Crossroads between bacterial and mammalian glycosyltransferases

Frontiers in Immunology, 2014
Bacterial glycosyltransferases often synthesize the same glycan linkages as mammalian glycosyltransferases, yet they usually have very little sequence identity.
Inka eBrockhausen
doaj   +2 more sources

Bacterial Glycosyltransferases: Challenges and opportunities of a highly diverse enzyme class toward tailoring natural products

Frontiers in Microbiology, 2016
The enzyme subclass of glycosyltransferases (EC 2.4) currently comprises 97 families as specified by CAZy classification. One of their important roles is in the biosynthesis of disaccharides, oligosaccharides and polysaccharides by catalyzing the ...
Jochen eSchmid, Dominik eHeider, Norma J. Wendel, Nadine eSperl, Volker eSieber   +4 more
doaj   +2 more sources

Glycosyltransferases encoded by viruses.

Journal of General Virology, 2004
peer reviewedStudies of cellular biology in recent decades have highlighted the crucial roles of glycans in numerous important biological processes, raising the concept of glycomics that is now considered as important as genomics, transcriptomics and ...
Verma, Naresh, Naresh Verma, Nicolas Markine-Goriaynoff, Laurent Gillet, Alain Vanderplasschen, Korres, Haralambos, Gillet, Laurent, Van Etten, James, Van Etten, James L, Markine-Goriaynoff, Nicolas, Haralambos Korres, James L. Van Etten, Van Etten, James L., Vanderplasschen, Alain   +13 more
core   +4 more sources

Exploring genomes for glycosyltransferases

Molecular BioSystems, 2010
International audienceGlycosyltransferases are one of the largest and most diverse enzyme groups in Nature. They catalyse the synthesis of glycosidic linkages by the transfer of a sugar residue from a donor to an acceptor substrate.
Hansen, Sara Fasmer, Engelsen, Søren, Søren B. Engelsen, Engelsen, Søren Balling, Breton, Christelle, Sara Fasmer Hansen, Emmanuel Bettler, Åsmund Rinnan, Christelle Breton, Bettler, Emmanuel, Fasmer Hansen, Sara, Rinnan, Åsmund   +11 more
core   +4 more sources

Effector Glycosyltransferases in Legionella [PDF]

Frontiers in Microbiology, 2011
Legionella causes severe pneumonia in humans. The pathogen produces an array of effectors, which interfere with host cell functions. Among them are the glucosyltransferases Lgt1, Lgt2 and Lgt3 from L. pneumophila. Lgt1 and Lgt2 are produced predominately in the post-exponential phase of bacterial growth, while synthesis of Lgt3 is induced mainly in the
Belyi, Yury, Jank, Thomas, Aktories, Klaus   +2 more
openaire   +4 more sources

Structural and functional investigation of Glycocin-Glycosyltransferases [PDF]

, 2023
Antimicrobial peptides are an interesting class on ribosomally and non-ribosomally synthesised peptides found in all kingdoms of life. Among these is the underexplored class of bacteriocins: Short ribosomally synthesized and post-translationally modified
Krummhaar, M., Krummhaar, Michael
core   +1 more source

Glycosyltransferases as Markers for Early Tumorigenesis [PDF]

, 2015
Background. Glycosylation is the most frequent posttranslational modification of proteins and lipids influencing inter-and intracellular communication and cell adhesion.
Liesche, Friederike, Ilmer, Matthias, Kölbl, Alexandra C., Jeschke, Udo, Andergassen, Ulrich, Hutter, Stefan, Friese, Klaus   +6 more
core   +1 more source

A quantitative study of the Golgi retention of glycosyltransferases

, 2021
How Golgi glycosyltransferases and glycosidases (hereafter glycosyltransferases) localize to the Golgi is still unclear. Here, we first investigated the post-Golgi trafficking of glycosyltransferases.
Mahajan, Divyanshu, Chen, Bing, Sun, Xiuping, Song, Zhiwei, Lu, Lei   +4 more
core   +1 more source

Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei [PDF]

, 2014
Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans.
Damerow, Manuela, Ferguson, Michael A. J.; id_orcid, Güther, M. Lucia S., Wu, Di, Mehlert, Angela, Rodrigues, Joao A.   +5 more
core   +1 more source

Family 1 glycosyltransferases (GT1, UGTs) are subject to dilution-induced inactivation and low chemo stability towards their own acceptor substrates

, 2022
Glycosylation reactions are essential but challenging from a conventional chemistry standpoint. Conversely, they are biotechnologically feasible as glycosyltransferases can transfer a sugar to an acceptor with perfect regio- and stereo- selectivity ...
Gonzalo, Bidart, Ditte, Welner, David, Teze   +2 more
core   +1 more source