Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
In vitro and molecular characterization using ISSR markers of Glycyrrhiza glabra L.
Licorice ( Glycyrrhiza glabra ) is the rhizome and root known as sweet wood. Two varieties of Glycyrrhiza (var. glabra and var. glandulifera ) were studied.
Asmaa Abd El-Hameid +3 more
doaj +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
Oral Ulcerations and Phytotherapy: Potential Role of Helichrysum Essential Oil—A Literature Review
ABSTRACT Background Recurrent aphthous stomatitis (RAS) is a common yet therapeutically challenging chronic inflammatory disease of the oral mucosa, characterized by recurrent, painful ulcerations that substantially affect patients' quality of life. Objective This review summarizes current evidence on phytotherapy in RAS, with particular focus on the ...
Ruzica Ivkovic +4 more
wiley +1 more source
In Silico Screening Inhibitors Histamine H2 Chemical Compounds in Licorice Plants (Glycyrrhiza glabra L.) Using Autodock Vina [PDF]
The inquiry about on in silico screening of chemical compounds of Histamine H2 of Liquorice (Glycyrrhiza glabra L.), aimed to get the potential bioactive compounds found in plants The Liquorice (Glycyrrhiza glabra L.) as a potential inhibitor Histamine ...
Malik, Abd. +2 more
core +1 more source
This study develops an ensemble‐based machine learning approach to detect and predict psychological disorders in menopausal women using clinical and questionnaire data. Random Forest achieved the best performance. The framework supports early risk identification and integrates statistical validation with Unani‐based and home remedy interventions to ...
Md Belal Bin Heyat +4 more
wiley +1 more source
Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
wiley +1 more source
This study evaluates Xiaoyaosan (XYS) for bipolar disorder (BD) using network pharmacology and experimental validation. Molecular docking reveals interactions between active XYS compounds and potential core targets. Animal experiments confirm XYS alleviates BD‐like behaviors in mice by suppressing core targets, elucidating its multi‐target mechanism ...
Man Chen +10 more
wiley +1 more source
Potensi Ekstrak Akar Manis (Glycyrrhiza Glabra) Pada Penyembuhan Lesi Ulserasi Recurrent Aphthous Stomatitis : Systematic Review [PDF]
Latar Belakang: Recurrent aphthous stomatitis (RAS) merupakan lesi yang umum ditemukan pada mukosa rongga mulut berupa ulkus berukuran kecil yang terasa nyeri yang berlangsung selama 7 hingga 14 hari dan mengganggu kualitas hidup pasien.
Annisa Sabrina Iskandar, -
core
IN VITRO EVALUATION OF ANTI MYCOTIC ACTIVITY OF ETHANOLIC EXTRACT OF GLYCYRRHIZA GLABRA [PDF]
Objective: The aim of the present study was to assess the anti fungal activity of ethanolic extract of Glycyrrhiza glabra. Glycyrrhiza glabra commonly called as liquorice or sweet root is one of the oldest known herbal remedies famous for its vast ...
GEETHA, R.V, ANITHA, ROY
core +1 more source

