Results 61 to 70 of about 14,063 (274)
Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice) [PDF]
, 2005 Carbenoxolone (CBX), the succinyl ester of glycyrrhetinic acid, is an inhibitor of gap junctional intercellular communication. We have tested its possible effects upon two genetic animal models of epilepsy (WAG/Rij rats and lethargic (lh/lh) mice ...
Barresi, V. +9 more
core +1 more source
Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia [PDF]
, 2020 Background: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer-associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy
Chiappalupi, S. +9 more
core +1 more source
Veterinary Dermatology, EarlyView.ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Adrian Watson +5 more
wiley +1 more source
Effects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism
Pharmaceutical Biology, 2018 Context: Asiatic acid has been reported to possess a wide range of pharmacological activities. Objective: This study investigates the effects of glycyrrhizin on the pharmacokinetics of asiatic acid in rats and its potential mechanism.
Ling Guo, Ying Cui, Kaijun Hao
doaj +1 more source
BMC Complementary Medicine and Therapies, 2023 Background Streptococcus mutans is a bacterium that causes oral diseases. Plaque, a biofilm produced by S. mutans and other bacteria, makes it difficult to remove cariogenic oral microorganisms, including biofilm producers.
Youngseok Ham, Tae-Jong Kim
doaj +1 more source
Phytochemicals in the Prevention and Treatment of SARS-CoV-2—Clinical Evidence
Antibiotics, 2022 The first case of SARS-CoV-2 infection was reported in December 2019. Due to the rapid spread of the disease and the lack of adequate therapy, the use of plants that have a long history in the treatment of viral infections has often been considered.
Katarina Bijelić +2 more
doaj +1 more source
Biomedicines, 2023 This study aimed to prepare glycyrrhizin–apigenin spray-dried solid dispersions and develop PVA filament-based 3D printlets to enhance the dissolution and therapeutic effects of apigenin (APN); three formulations (APN1–APN3) were proportioned from 1:1 to
Asma B. Omer +6 more
doaj +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan +6 more
wiley +1 more source
Hepatotprotective Natural Products [PDF]
, 2005 Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential.
Malhotra, Samir, Singh, Amrit Pal
core +1 more source
Dualistic Roles of High Mobility Group Box 1 in Cancer and Inflammation
Cancer Medicine, Volume 14, Issue 23, December 2025.ABSTRACT Background The High Mobility Group Box 1 (HMGB1) protein, a member of the HMG family, plays a crucial role in both cancer progression and inflammatory responses. HMGB1 can act as a damage‐associated molecular pattern (DAMP) to activate immune responses and modulate inflammation.
Wen Zeng +6 more
wiley +1 more source