Results 131 to 140 of about 11,518 (273)

40 Hz light flickering facilitates the glymphatic flow via adenosine signaling in mice

Cell Discovery
The glymphatic-lymphatic system is increasingly recognized as fundamental for the homeostasis of the brain milieu since it defines cerebral spinal fluid flow in the brain parenchyma and eliminates metabolic waste.
Xiaoting Sun, Liliana Dias, Chenlei Peng, Ziyi Zhang, Haoting Ge, Zejun Wang, Jiayi Jin, Manli Jia, Tao Xu, Wei Guo, Wu Zheng, Yan He, Youru Wu, Xiaohong Cai, Paula Agostinho, Jia Qu, Rodrigo A. Cunha, Xuzhao Zhou, Ruiliang Bai, Jiang-fan Chen   +19 more
doaj   +1 more source

Aquaporin-4 cerebrospinal fluid levels are higher in neurodegenerative dementia: looking at glymphatic system dysregulation [PDF]

, 2022
Andrea Arighi, Marina Arcaro, Giorgio Fumagalli, Tiziana Carandini, Anna M. Pietroboni, Luca Sacchi, Chiara Fenoglio, María Serpente, Federica Sorrentino, Giovanni Isgrò, Federico Turkheimer, Elio Scarpini, Daniela Galimberti   +12 more
openalex   +1 more source

Sympathetic innervation of human cervical lymph nodes: A potential neuroimmunomodulatory target for the treatment of T‐cell‐driven autoimmune diseases like MS?

Journal of Anatomy, EarlyView.
Recent animal studies have shown that the sympathetic nervous system (SNS) prevents disease activity of EAE (Experimental autoimmune encephalomyelitis, animal model of Multiple Sclerosis [MS]), presumably through adrenergic activity in the deep cervical lymph nodes (DCLNs).
Christopher Kremer, Claire Mackaaij, Suzanne A. M. W. Verlinde‐Schellekens, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +4 more
wiley   +1 more source

Dynamic Evolution of the Glymphatic System at the Early Stages of Subarachnoid Hemorrhage [PDF]

, 2022
Changkai Hou, Jian Li, Bangyue Wang, Quanlei Liu, Yan Zhao, Hao Zhang, Weihan Wang, Wen Ren, Xiaopeng Cui, Xinyu Yang   +9 more
openalex   +1 more source

Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén, Anna Lindam, Dan Farahmand, Anne‐Marie Landtblom, Katarina Laurell   +4 more
wiley   +1 more source

Glymphatic system and mild traumatic brain injury: a mini review

Frontiers in Neuroscience
Since the discovery of the glymphatic system in 2012, research on this brain-wide fluid exchange pathway has focused on understanding its role in different neurological diseases.
Pihla Miettinen, Begüm Utz, Ivette Bañuelos-Cabrera, Eugene Golanov, Ziv Lenzner, Leonardo Lara-Valderrábano, Lasse Välimaa, Adrian Harel   +7 more
doaj   +1 more source

Whole-brain imaging of the glymphatic system–a new strategy to investigate amyloid clearance in AD [PDF]

, 2013

openalex   +1 more source

General Anesthesia Inhibits the Activity of the “Glymphatic System”

Theranostics, 2018
INTRODUCTION: According to the "glymphatic system" hypothesis, brain waste clearance is mediated by a continuous replacement of the interstitial milieu by a bulk flow of cerebrospinal fluid (CSF). Previous reports suggested that this cerebral CSF circulation is only active during general anesthesia or sleep, an effect mediated by the dilatation of the ...
Jennifer Bourgès, Clément Gakuba, Maxime Gauberti, Thomas Gaberel, Suzanne Goursaud, Denis Vivien, Sara Martinez de Lizarrondo, Camille Di Palma, Aurélien Quenault   +8 more
openaire   +2 more sources

Sleep neuroimaging: Review and future directions

Journal of Sleep Research, EarlyView.
Summary Sleep research has evolved considerably since the first sleep electroencephalography recordings in the 1930s and the discovery of well‐distinguishable sleep stages in the 1950s. While electrophysiological recordings have been used to describe the sleeping brain in much detail, since the 1990s neuroimaging techniques have been applied to uncover
Mariana Pereira, Xinyuan Chen, Anastasiya Paltarzhytskaya, Yibran Pacheсo, Nils Muller, Leonore Bovy, Xu Lei, Wei Chen, Haoran Ren, Chen Song, Laura D. Lewis, Thien Thanh Dang‐Vu, Michael Czisch, Dante Picchioni, Jeff Duyn, Philippe Peigneux, Enzo Tagliazucchi, Martin Dresler   +17 more
wiley   +1 more source

MRI‐based surrogates of brain clearance in narcolepsy type 1

Journal of Sleep Research, EarlyView.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese, Jari K. Gool, Gert Jan Lammers, Ysbrand D. van der Werf, Matthias J. P. van Osch, Rolf Fronczek, Lydiane Hirschler   +6 more
wiley   +1 more source