Results 151 to 160 of about 24,909,638 (279)

A lifespan staging model of basal forebrain cholinergic vulnerability

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The cholinergic neurons of the basal forebrain are among the most vulnerable cell types to age‐ and Alzheimer's disease‐related dysfunction and neurodegeneration. However, the biological bases of basal forebrain cholinergic vulnerability (the why) and the temporal sequence (the how) have yet to be fully resolved.
Hayley R. C. Shanks, Sherry Chen, Kate M. Onuska, Taylor W. Schmitz   +3 more
wiley   +1 more source

Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery. [PDF]

Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA.
Akbari, Yama, Bazrafkan, Afsheen, Choi, Bernard, Crouzet, Christian, Lee, Donald, Tromberg, Bruce J, Wilson, Robert H   +6 more
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Watching the eye with Mars in sight

Experimental Physiology, EarlyView.
Peter zu Eulenburg, Lonnie Petersen, Damian M. Bailey   +2 more
wiley   +1 more source

Associations among sleep quality, cognitive decline, and Alzheimer's disease pathology in older adults: A longitudinal study

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION This study aimed to investigate whether sleep quality predicts cognitive/functional decline, and whether Alzheimer's disease (AD) pathology modifies these relationships. METHODS The Pittsburgh Sleep Quality Index was administered to 326 older adults (113 cognitively normal, 192 mild cognitive impairment, 21 dementia; mean age = 66.
Layaly Shihadeh, Mónica Rosselli, Joshua Conniff, Breton Asken, Alicia Goytizolo, Warren Barker, Emily F. Matusz, Angel Collie, Stephen A. Coombes, Melissa Armstrong, Idaly Velez‐Uribe, Malek Adjouadi, Glenn E. Smith, Ranjan Duara, Steven D. DeKosky, David A. Loewenstein   +15 more
wiley   +1 more source

Meningeal Lymphatic and Glymphatic Structures in a Pelagic Delphinid (Delphinus delphis)

Animals
The glymphatic system, an analog of the peripheral lymphatic system in the brain, and the meningeal lymphatic system are critical to central nervous system health.
Olivia N. Jackson, Tiffany F. Keenan, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Victoria G. Thayer, Craig A. Harms, Marina A. Piscitelli-Doshkov, Paul Doshkov, Lorian E. Schweikert, Kara E. Yopak, Molly Braun, Michael S. Tift   +17 more
doaj   +1 more source

Evidence for direct and sleep‐moderated relationships between aquaporin‐4 genetic variants and Alzheimer's disease phenotypes

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Variants in the aquaporin‐4 gene (AQP4) have been associated with Alzheimer's disease (AD) diagnosis, cognition, and brain amyloid beta (Aβ) and may affect the sleep and Aβ relationship. Their association with other AD‐related phenotypes/disease progression remain largely unknown.
Tenielle Porter, Ayeisha Milligan Armstrong, Eleanor K. O'Brien, Vincent Doré, Pierrick Bourgeat, Mitchell Turner, Paul Maruff, Christopher C. Rowe, Belinda M. Brown, Victor L. Villemagne, Stephanie R. Rainey‐Smith, Simon M. Laws, AIBL Research Group   +12 more
wiley   +1 more source

Water and wisdom: Hydration as a defence against dementia

Experimental Physiology, EarlyView.
David C. Byfield, Damian M. Bailey
wiley   +1 more source

Association of imaging‐defined brain age with disease severity and adverse outcomes in CADASIL

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by cysteine‐altering NOTCH3 variants. We examined whether neuroimaging‐defined brain age is altered in CADASIL and its association with disease severity and outcomes.
Shao‐Lun Hsu, Pei‐Lin Lee, Kun‐Hsien Chou, Chen‐Yuan Kuo, Ching‐Po Lin, Yi‐Chu Liao, Chih‐Ping Chung, Yi‐Chung Lee   +7 more
wiley   +1 more source

Morphology of the glymphatic and meningeal lymphatic structures of the bottlenose dolphin

Scientific Reports
In humans and mice, the glymphatic system, critical for central nervous system (CNS) health, relies on cardiorespiratory coupling, but has not yet been investigated in a diving mammal that routinely experiences apnea, bradycardia, and peripheral ...
Tiffany F. Keenan, Olivia N. Jackson, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Molly Braun, Michael S. Tift   +11 more
doaj   +1 more source

A CFD and FEM Approach to a Multicompartmental Poroelastic Model for CSF Production and Circulation with Applicationsin Hydrocephalus Treatment and Cerebral Oedema [PDF]

This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Chou, D, Tully, BJ, Vardakis, JC, Ventikos, Y   +4 more
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