Results 131 to 140 of about 9,639 (217)

Task‐Evoked Functional Activation and Coupling With CSF Flow Detected in the Human Brain With Ultrashort Echo Time fMRI at 7 T

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Ultrashort and zero echo time (UTE and ZTE) MRI techniques generate functional contrast through inflow effects, making them suitable for studying cerebral blood flow and cerebrospinal fluid (CSF) dynamics. In a 7‐T study of 13 participants performing a visual task, we demonstrate that UTE produced robust, reproducible activations with group‐level ...
Sara Ponticorvo, Ekaterina Paasonen, Pavel Filip, Douglas L. Rothman, Juha S. Valjakka, Olli Gröhn, Shalom Michaeli, Silvia Mangia   +7 more
wiley   +1 more source

Targeting the glymphatic system: Aβ accumulation and phototherapy strategies across different stages of Alzheimer’s disease

Translational Neurodegeneration
The glymphatic system serves as the brain’s clearance system. It deteriorates with age and is a significant contributor to the onset and progression of Alzheimer’s disease (AD).
Danrui Zhao, Junting Wang, Yirui Zhu, Hao Zhang, Chenkang Ni, Zhuowen Zhao, Jingyu Dai, Rongqiao He, Guangzhi Liu, Cheng Gan, Shouzi Zhang, Zhiqian Tong   +11 more
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

The Glymphatic System: A New Player in Ocular Diseases? [PDF]

Investigative Opthalmology & Visual Science, 2016
Wostyn, Peter, De Groot, Veva, Van Dam, Debby, Audenaert, Kurt, De Deyn, Peter Paul, Killer, Hanspeter Esriel   +5 more
openaire   +3 more sources

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

Glymphatic activity is linked to the synaptic vesicle cycle pathway in frontotemporal dementia: A metabolomics study

Neurobiology of Disease
Background: Emerging evidence implicating glymphatic dysfunction contributes to the pathogenesis of frontotemporal dementia (FTD). However, the pathway correlated to glymphatic function in FTD remains poorly understood.
Min Chu, Ailing Yue, Haitian Nan, Hong Ye, Miao Qu, Liyong Wu   +5 more
doaj   +1 more source

Overnight Dynamics of Ventricular Cerebrospinal Fluid Amyloid‐Beta, Lactate and Hypocretin in Patients With Hydrocephalus: A Pilot Study

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT This pilot observational study evaluated whether frequent overnight sampling of ventricular cerebrospinal fluid could clarify how sleep, hypocretin and lactate relate to amyloid‐β42 dynamics in adults with hydrocephalus. Seven participants underwent hourly ventricular cerebrospinal fluid sampling from early evening to late morning during ...
Casper Schwartz Riedel, Joachim Birch Milan, Niklas Rye Jørgensen, Poul Jennum, Marianne Juhler   +4 more
wiley   +1 more source

An Electroencephalographic Study of Sleep Spindle and Infraslow Oscillation in Children With Autism Spectrum Disorder

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT We investigated whether sleep microstructures show spatial differences in young children with autism compared with typically developing peers. 32‐channel electroencephalography (EEG) during natural sleep after 5–6 h of partial sleep deprivation was recorded from 53 children (26 with autism, 27 typically developing; 1.1–5.1 years).
Kevin Liu, Binbin Sun, Bryan K. Wang, Jonathan Chen, M. Brandon Westover, Fu‐Ying Tian, Haoqi Sun, Xue‐Jun Kong   +7 more
wiley   +1 more source

Role of the glymphatic system in ageing and diabetes mellitus impaired cognitive function [PDF]

, 2019
Diabetes mellitus (DM) is a common metabolic disease in the middle-aged and older population, and is associated with cognitive impairment and an increased risk of developing dementia.
Zhang, Zhenggang, Zhang, Li, Jiang, Quan, Chopp, Michael   +3 more
core  

Morphology of the glymphatic and meningeal lymphatic structures of the bottlenose dolphin

Scientific Reports
In humans and mice, the glymphatic system, critical for central nervous system (CNS) health, relies on cardiorespiratory coupling, but has not yet been investigated in a diving mammal that routinely experiences apnea, bradycardia, and peripheral ...
Tiffany F. Keenan, Olivia N. Jackson, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Molly Braun, Michael S. Tift   +11 more
doaj   +1 more source