Results 141 to 150 of about 12,211 (230)

Effect of a Single Oral Dose of Dexamphetamine or Zolpidem on Attention and Reaction Time in Healthy Men

Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.
ABSTRACT Psychotropic medicines are known to impair cognitive function acutely, but the specific effects of individual substances remain underexplored. This study investigates the effects of dexamphetamine and zolpidem on cognitive performance to quantify the potential risk of intake and their pharmacokinetic and pharmacodynamic relationship.
Veronika Pfoser‐Poschacher, Michael Wolf, Michaela Bayerle‐Eder, Teresa Wimmer, Daniela Boryshchuk, Christopher Gerner, Michael Wolzt   +6 more
wiley   +1 more source

Glymphatic system waste clearance and Alzheimer's disease

Brazilian Journal of Psychiatry, 2023
Joao Luis Barichello de Quevedo, Douglas Teixeira Leffa, Tharick A. Pascoa   +2 more
openaire   +5 more sources

The glymphatic system and glioblastoma

Brain
Abstract The discovery of the glymphatic system and meningeal lymphatic vessels revolutionized the understanding of brain waste clearance. These findings challenged the long-held notion of central nervous system (CNS) immune privilege and provided insights into how the brain maintains homeostasis despite lacking conventional lymphatic
Andrea Soumbasis, Aito Ueno, David Elliott, Sanju Lama, Sarah Edwards, Yves P Starreveld, Yunyan Zhang, Paolo Federico, Garnette R Sutherland, Pierre LeVan, Candice C Poon   +10 more
openaire   +1 more source

Correlation between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in type 2 diabetes mellitus

Journal of Diabetes Investigation, Volume 17, Issue 5, Page 844-850, May 2026.
ABSTRACT Aims To determine the relationship between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in patients with type 2 diabetes mellitus. Materials and Methods Cranial magnetic resonance imaging data from 200 patients with type 2 diabetes mellitus were analyzed to categorize enlarged perivascular spaces in the basal ganglia and
Wei Zhang, Zhen Wang, Yaping Sun, Shaofeng Xu, Lei Zhu, Xiaolei Li   +5 more
wiley   +1 more source

Diffusion–tensor MRI study of the relationship between glymphatic system asymmetry and onset lateralization in Parkinson’s disease

npj Parkinson's Disease
The characteristic asymmetric motor symptoms of Parkinson’s disease (PD) may be associated with asymmetric deposition of α-synuclein. The impaired glymphatic system may promote pathological deposition of α-synuclein, leading to disease progression.
Zihan Li, Xinxin Miao, Qiumei Zhang, Jun Shen, Yongfeng Jia, Shaoyun Ge, Peixian Ji, Jianwei Wang, Kezhong Zhang, Min Wang   +9 more
doaj   +1 more source

Glymphatic activity is linked to the synaptic vesicle cycle pathway in frontotemporal dementia: A metabolomics study

Neurobiology of Disease
Background: Emerging evidence implicating glymphatic dysfunction contributes to the pathogenesis of frontotemporal dementia (FTD). However, the pathway correlated to glymphatic function in FTD remains poorly understood.
Min Chu, Ailing Yue, Haitian Nan, Hong Ye, Miao Qu, Liyong Wu   +5 more
doaj   +1 more source

Morphology of the glymphatic and meningeal lymphatic structures of the bottlenose dolphin

Scientific Reports
In humans and mice, the glymphatic system, critical for central nervous system (CNS) health, relies on cardiorespiratory coupling, but has not yet been investigated in a diving mammal that routinely experiences apnea, bradycardia, and peripheral ...
Tiffany F. Keenan, Olivia N. Jackson, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Molly Braun, Michael S. Tift   +11 more
doaj   +1 more source

“Hypodense Holes” and the Ocular Glymphatic System: Author Response: “Black Holes” and the Ocular Glymphatic System [PDF]

Investigative Opthalmology & Visual Science, 2017
Wostyn, Peter, De Groot, Veva, Van Dam, Debby, Audenaert, Kurt, De Deyn, Peter Paul, Esriel Killer, Hanspeter   +5 more
openaire   +3 more sources

Insights into glymphatic system dysfunction and glucose continuum

World Journal of Diabetes
In this article, we comment on an original article published in a recent issue of the World Journal of Diabetes . That observational cross-sectional study focused on investigating the function of the glymphatic system and its clinical correlates in patients with different glucose metabolism states by using diffusion tensor imaging along the ...
Velikova, Tsvetelina, Vasilev, Georgi
openaire   +2 more sources

"Black Holes" and the Ocular Glymphatic System: Author Response to "The Glymphatic System: A New Player in Ocular Diseases?" [PDF]

, 2016
Denniston, AK, Keane, PA
core   +1 more source