Results 141 to 150 of about 12,498 (256)

Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy. [PDF]

, 2018
Malignant gliomas carry a dismal prognosis. Conventional treatment using chemo- and radiotherapy has limited efficacy with adverse events. Therapy with genetically engineered T-cells, such as chimeric antigen receptor (CAR) T-cells, may represent a ...
Almeida, Neil D, Chuntova, Pavlina, Downey, Kira M, Hegde, Bindu, Okada, Hideho   +4 more
core  

Watching the eye with Mars in sight

Experimental Physiology, EarlyView.
Peter zu Eulenburg, Lonnie Petersen, Damian M. Bailey   +2 more
wiley   +1 more source

No Glymphatic Dysfunction in Trigeminal Neuralgia: A Preliminary Study

Brain and Behavior, Volume 16, Issue 2, February 2026.
In this study investigating cross‐sectional and longitudinal DTI‐ALPS changes in patients with trigeminal neuralgia, no DTI‐ALPS alterations were detected in trigeminal neuralgia patients. ABSTRACT Background Trigeminal neuralgia (TN) patients are at risk for glymphatic dysfunction due to their prolonged headaches and sleep disturbances.
Barış Genç, Kerim Aslan
wiley   +1 more source

"Black Holes" and the Ocular Glymphatic System: Author Response to "The Glymphatic System: A New Player in Ocular Diseases?" [PDF]

, 2016
Denniston, AK, Keane, PA
core   +1 more source

Changes in the glymphatic system before and after dialysis initiation in patients with end-stage kidney disease

, 2023
Yoo Jin Lee, Kang Min Park, Chang Min Heo, Sihyung Park, Yang Wook Kim, Dongyeol Lee, Yunmi Kim, Joon Seok Oh, Ho Sik Shin, Bong Soo Park   +9 more
openalex   +1 more source

Water and wisdom: Hydration as a defence against dementia

Experimental Physiology, EarlyView.
David C. Byfield, Damian M. Bailey
wiley   +1 more source

Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC

Glia, Volume 74, Issue 2, February 2026.
Mechanical properties of Mlc1‐null astrocytes are altered. Cytoskeleton‐related pathways are dysregulated in Mlc1‐null astrocytes. Mlc1‐null astrocytes show alterations in focal adhesions, which link the cytoskeleton to the extracellular matrix. ABSTRACT Loss of function of the astrocyte protein MLC1 causes Megalencephalic Leukoencephalopathy with ...
Quinty Bisseling, Emma M. J. Passchier, Freya M. Kirwan, Nelda Antonovaite, Serena Camerini, Maria S. Brignone, Amélie Freal, Huibert D. Mansvelder, Elena Ambrosini, Marjo S. van der Knaap, Rogier Min   +10 more
wiley   +1 more source

Diffusion–tensor MRI study of the relationship between glymphatic system asymmetry and onset lateralization in Parkinson’s disease

npj Parkinson's Disease
The characteristic asymmetric motor symptoms of Parkinson’s disease (PD) may be associated with asymmetric deposition of α-synuclein. The impaired glymphatic system may promote pathological deposition of α-synuclein, leading to disease progression.
Zihan Li, Xinxin Miao, Qiumei Zhang, Jun Shen, Yongfeng Jia, Shaoyun Ge, Peixian Ji, Jianwei Wang, Kezhong Zhang, Min Wang   +9 more
doaj   +1 more source

Glymphatic activity is linked to the synaptic vesicle cycle pathway in frontotemporal dementia: A metabolomics study

Neurobiology of Disease
Background: Emerging evidence implicating glymphatic dysfunction contributes to the pathogenesis of frontotemporal dementia (FTD). However, the pathway correlated to glymphatic function in FTD remains poorly understood.
Min Chu, Ailing Yue, Haitian Nan, Hong Ye, Miao Qu, Liyong Wu   +5 more
doaj   +1 more source

Comparative analysis of glymphatic system alterations in multiple sclerosis and neuromyelitis optica spectrum disorder using MRI indices from diffusion tensor imaging [PDF]

Minchul Kim, Inpyeong Hwang, Jung‐Hyun Park, Jin Wook Chung, Sung Min Kim, Ji‐hoon Kim, Kyu Sung Choi   +6 more
openalex   +1 more source