Results 31 to 40 of about 11,518 (273)
The Glymphatic System (En)during Inflammation [PDF]
International Journal of Molecular Sciences, 2021 The glymphatic system is a fluid-transport system that accesses all regions of the brain. It facilitates the exchange of cerebrospinal fluid and interstitial fluid and clears waste from the metabolically active brain. Astrocytic endfeet and their dense expression of the aquaporin-4 water channels promote fluid exchange between the perivascular spaces ...
Frida Lind-Holm Mogensen +2 more
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Frontiers in Aging Neuroscience, 2021 Perioperative neurocognitive disorder (PND) frequently occurs in the elderly as a severe postoperative complication and is characterized by a decline in cognitive function that impairs memory, attention, and other cognitive domains.
Xuli Ren +7 more
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The Brain’s Glymphatic System: Drawing New Perspectives in Neuroscience
Brain Sciences, 2023 This paper delves into the intricate structure and functionality of the brain’s glymphatic system, bringing forth new dimensions in its neuroscientific understanding.
Alexandru Vlad Ciurea +4 more
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Glymphatic system and aquaporin‑4 in epilepsy
Acta Neurobiologiae Experimentalis, 2023 Over the past decade glymphatic concept has gained more and more interest. Despite some lacking data regarding structural and functional aspects, glymphatic system is widely considered the main mechanism of water and solutes transport in brain parenchyma, as well as waste clearance from the brain.
Dorota Nowicka
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Wasteosomes (corpora amylacea) as a hallmark of chronic glymphatic insufficiency [PDF]
, 2023 In different organs and tissues, the lymphatic system serves as a drainage system for interstitial fluid and is useful for removing substances that would otherwise accumulate in the interstitium.
Molina Porcel, Laura +4 more
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Mapping the Glymphatic Pathway Using Imaging Advances
J, 2023 The glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e ...
Rajvi N. Thakkar +6 more
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The Glymphatic System: A Review [PDF]
Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, 2018 AbstractThe brain represents ∼ 2% of the adult body mass; conversely, it is responsible for 20% to 25% of the glucose and 20% of the oxygen consumption, receiving 15% of the cardiac output. This substantial metabolic rate is associated with a significant production of biological debris, which is potentially toxic.
Louise Makarem Oliveira +2 more
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Mediators of Inflammation, 2022 Amyloid-β (Aβ) deposition plays a crucial role in the occurrence and development of Alzheimer’s disease (AD), and impaired Aβ clearance is the leading cause of Aβ deposition.
Cheng Wu +11 more
doaj +1 more source
The Brain’s Glymphatic System: Current Controversies [PDF]
Trends in Neurosciences, 2020 The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in recent years, highlighted that fluid is directionally transported within the central nervous system (CNS). Imaging studies, as well as manipulations of fluid transport, point to a key role of the glymphatic-lymphatic system in clearance of amyloid-β and other ...
Mestre, Humberto +2 more
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The Glymphatic System: A Beginner’s Guide [PDF]
Neurochemical Research, 2015 The glymphatic system is a recently discovered macroscopic waste clearance system that utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote efficient elimination of soluble proteins and metabolites from the central nervous system.
Nadia Aalling Jessen +3 more
openaire +3 more sources