Results 31 to 40 of about 12,498 (256)
Glymphatic System Dysfunction in Central Nervous System Diseases and Mood Disorders
Frontiers in Aging Neuroscience, 2022 The glymphatic system, a recently discovered macroscopic waste removal system in the brain, has many unknown aspects, especially its driving forces and relationship with sleep, and thus further explorations of the relationship between the glymphatic ...
Dianjun Zhang +8 more
doaj +1 more source
The Glymphatic System (En)during Inflammation [PDF]
International Journal of Molecular Sciences, 2021 The glymphatic system is a fluid-transport system that accesses all regions of the brain. It facilitates the exchange of cerebrospinal fluid and interstitial fluid and clears waste from the metabolically active brain. Astrocytic endfeet and their dense expression of the aquaporin-4 water channels promote fluid exchange between the perivascular spaces ...
Frida Lind-Holm Mogensen +2 more
openaire +4 more sources
The Glymphatic System and Pain [PDF]
Medical Acupuncture, 2020 The glymphatic system is network of perivascular spaces through which cerebrospinal fluid and interstitial fluid can move through the brain, clearing metabolic waste, such as amyloid beta, lactate and more, from the parenchyma. This cleaning system is regulated by sleep and norepinephrine, with increased levels of norepinephrine during wakefulness ...
Goldman, Nanna +3 more
openaire +3 more sources
Frontiers in Aging Neuroscience, 2021 Perioperative neurocognitive disorder (PND) frequently occurs in the elderly as a severe postoperative complication and is characterized by a decline in cognitive function that impairs memory, attention, and other cognitive domains.
Xuli Ren +7 more
doaj +1 more source
The Brain’s Glymphatic System: Drawing New Perspectives in Neuroscience
Brain Sciences, 2023 This paper delves into the intricate structure and functionality of the brain’s glymphatic system, bringing forth new dimensions in its neuroscientific understanding.
Alexandru Vlad Ciurea +4 more
doaj +1 more source
The Brain’s Glymphatic System: Current Controversies [PDF]
Trends in Neurosciences, 2020 The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in recent years, highlighted that fluid is directionally transported within the central nervous system (CNS). Imaging studies, as well as manipulations of fluid transport, point to a key role of the glymphatic-lymphatic system in clearance of amyloid-β and other ...
Mestre, Humberto +2 more
openaire +4 more sources
The glymphatic system: Current understanding and modeling [PDF]
iScience, 2022 We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models enable hypothesis development and predictions of transport, with clinical applications including drug delivery, stroke, cardiac arrest, and neurodegenerative disorders ...
Bohr, Tomas +18 more
openaire +8 more sources
Glymphatic system dysfunction mediates amyloid deposition and cognitive impairment in Alzheimer's disease: a PET/MRI multimodality imaging study. [PDF]
EJNMMI ResXue H +10 more
europepmc +2 more sources
Peristaltic flow in the glymphatic system [PDF]
Scientific Reports, 2020 AbstractThe flow inside the perivascular space (PVS) is modeled using a first-principles approach in order to investigate how the cerebrospinal fluid (CSF) enters the brain through a permeable layer of glial cells. Lubrication theory is employed to deal with the flow in the thin annular gap of the perivascular space between an impermeable artery and ...
Romano, Francesco +3 more
openaire +5 more sources
Hemodialysis and its effects on glymphatic system function in end-stage kidney disease patients. [PDF]
Quant Imaging Med SurgXiong Z +7 more
europepmc +2 more sources