Results 51 to 60 of about 11,518 (273)
Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation [PDF]
, 2016 Sleep deprivation reduces the dextran radial distribution and 125I-apoE inflow from CSF into brain. A-B) Representative images of cascade blue dextran (CB) in mice on normal sleep cycle (A) and in mice during sleep deprivation (SD) (B).
Achariyar, Thiyagaragan M +12 more
core +3 more sources
Impairment of the glymphatic system after diabetes [PDF]
Journal of Cerebral Blood Flow & Metabolism, 2016 The glymphatic system has recently been shown to clear brain extracellular solutes and abnormalities in glymphatic clearance system may contribute to both initiation and progression of neurological diseases. Despite that diabetes is known as a risk factor for vascular diseases, little is known how diabetes affects the glymphatic system.
Qingjiang Li +10 more
openaire +4 more sources
Can better management of periodontal disease delay the onset and progression of Alzheimer’s disease? [PDF]
, 2017 A risk factor relationship exists between periodontal disease and Alzheimer’s disease (AD) via tooth loss, and improved memory following dental intervention.
Crean, Stjohn +3 more
core +1 more source
The Ocular Glymphatic Clearance System [PDF]
, 2019 AbstractDespite high metabolic activity, the retina and optic nerve head lack traditional lymphatic drainage. We here identified a novel ocular glymphatic clearance route for fluid and wastes via the proximal optic nerve. Amyloid-β (Aβ) was cleared from the vitreous via a pathway driven by the ocular-cranial pressure difference.
Richard T. Libby +17 more
openaire +4 more sources
Perivascular Spaces, Glymphatic System and MR
Frontiers in Neurology, 2022 The importance of the perivascular space (PVS) as one of the imaging markers of cerebral small vessel disease (CSVD) has been widely appreciated by the neuroradiologists. The PVS surrounds the small blood vessels in the brain and has a signal consistent with the cerebrospinal fluid (CSF) on MR.
Linya Yu +3 more
openaire +3 more sources
Brain edema : a valid endpoint for measuring hepatic encephalopathy? [PDF]
, 2016 Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease.
Bémeur, Chantal +5 more
core +1 more source
Mechanically manipulating glymphatic transport by ultrasound combined with microbubbles [PDF]
, 2023 The glymphatic system is a perivascular fluid transport system for waste clearance. Glymphatic transport is believed to be driven by the perivascular pumping effect created by the pulsation of the arterial wall caused by the cardiac cycle.
Chen, Hong +6 more
core +2 more sources
The glymphatic system and subarachnoid hemorrhage: disruption and recovery
Exploration of Neuroprotective Therapy, 2022 The glymphatic system, or glial-lymphatic system, is a waste clearance system composed of perivascular channels formed by astrocytes that mediate the clearance of proteins and metabolites from the brain.
Stephan Quintin +4 more
doaj +1 more source
Glymphatic system, AQP4, and their implications in Alzheimer’s disease [PDF]
Neurological Research and Practice, 2021 AbstractLacking conventional lymphatic system, the central nervous system requires alternative clearance systems, such as the glymphatic system, which promotes clearance of interstitial solutes. Aquaporin-4 water channels (AQP4) are an integral part of this system and related to neuropathologies, such as Alzheimer’s disease (AD).
Inês Silva +3 more
openaire +4 more sources
Influencing factors of glymphatic system during perioperative period
Frontiers in NeuroscienceThe glymphatic system is a functional cerebrospinal fluid circulatory system that uses peri-arterial space for inflow of cerebrospinal fluid and peri-venous space for efflux of cerebrospinal fluid from brain parenchyma.
Rui Dong +8 more
doaj +1 more source