Results 51 to 60 of about 12,498 (256)
Astrocytic Ion Dynamics: Implications for Potassium Buffering and Liquid Flow [PDF]
, 2019 We review modeling of astrocyte ion dynamics with a specific focus on the implications of so-called spatial potassium buffering, where excess potassium in the extracellular space (ECS) is transported away to prevent pathological neural spiking.
A Destexhe +76 more
core +2 more sources
What Is the “Glymphatic System”?
Magnetic Resonance in Medical Sciences, 2023 Although the glymphatic system hypothesis is highly popular, it also lacks certain details. In this paper, an attempt was made to present a more clearly defined hypothesis, which is consistent with the past experiment results. The new hypothesis consists of (1) water flux in the brain parenchyma, (2) water and solutes pathway of the perivascular space,
openaire +3 more sources
Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation [PDF]
, 2016 Sleep deprivation reduces the dextran radial distribution and 125I-apoE inflow from CSF into brain. A-B) Representative images of cascade blue dextran (CB) in mice on normal sleep cycle (A) and in mice during sleep deprivation (SD) (B).
Achariyar, Thiyagaragan M +12 more
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Can better management of periodontal disease delay the onset and progression of Alzheimer’s disease? [PDF]
, 2017 A risk factor relationship exists between periodontal disease and Alzheimer’s disease (AD) via tooth loss, and improved memory following dental intervention.
Crean, Stjohn +3 more
core +1 more source
The Glymphatic System: A Beginner’s Guide [PDF]
Neurochemical Research, 2015 The glymphatic system is a recently discovered macroscopic waste clearance system that utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote efficient elimination of soluble proteins and metabolites from the central nervous system.
Nadia Aalling Jessen +3 more
openaire +2 more sources
The Role of Glymphatic System in Alzheimer’s and Parkinson’s Disease Pathogenesis
Biomedicines, 2022 Alzheimer’s disease (AD) is the most common cause of neurodegenerative dementia, whilst Parkinson’s disease (PD) is a neurodegenerative movement disorder.
Francesca R. Buccellato +4 more
doaj +1 more source
Frontiers in Neurology, 2022 Objective:The brain relies on the glymphatic system to clear metabolic wastes and maintain brain homeostasis to fulfill its functions better. Yet, the complexity of the glymphatic flow and clearance and its changes in HIV infection and its role in ...
Benedictor Alexander Nguchu +8 more
doaj +1 more source
Brain edema : a valid endpoint for measuring hepatic encephalopathy? [PDF]
, 2016 Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease.
Bémeur, Chantal +5 more
core +1 more source
Wasteosomes (corpora amylacea) as a hallmark of chronic glymphatic insufficiency [PDF]
, 2023 In different organs and tissues, the lymphatic system serves as a drainage system for interstitial fluid and is useful for removing substances that would otherwise accumulate in the interstitium.
Molina Porcel, Laura +4 more
core +1 more source
Astrocytes and neurons communicate via a monocarboxylic acid shuttle [PDF]
, 2020 Since formulation of the Astrocyte-Neuron Lactate Shuttle (ANLS) hypothesis in 1994, the hypothesis has provoked criticism and debate. Our review does not criticise, but rather integrates experimental data characterizing proton-linked monocarboxylate ...
Cottrell, Graeme S., Roosterman, Dirk
core +1 more source