Results 71 to 80 of about 18,116,541 (240)

SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline

open access: yes, 2022
Repository for original code used in research article    "SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline"
Marko Rosenholm (13814824)
core   +1 more source

The role and mechanism of Aβ clearance dysfunction in the glymphatic system in Alzheimer’s disease comorbidity

open access: yesFrontiers in Neurology
Alzheimer’s disease (AD) is the leading type of dementia globally, characterized by a complex pathogenesis that involves various comorbidities. An imbalance in the production and clearance of amyloid β-protein (Aβ) peptides in the brain is a key ...
Hailang Li   +4 more
doaj   +1 more source

Neurosurgery and the glymphatic system

open access: yesActa Neurochirurgica
Abstract The discovery of the glymphatic system has fundamentally altered our comprehension of cerebrospinal fluid transport and the removal of waste from brain metabolism. In the past decade, since its initial characterization, research on the glymphatic system has surged exponentially.
openaire   +2 more sources

Glymphatic system and aquaporin‑4 in epilepsy

open access: yesActa Neurobiologiae Experimentalis, 2023
Over the past decade glymphatic concept has gained more and more interest. Despite some lacking data regarding structural and functional aspects, glymphatic system is widely considered the main mechanism of water and solutes transport in brain parenchyma, as well as waste clearance from the brain.
openaire   +2 more sources

Potential value of slow‐wave sleep in management of chronic insomnia disorder

open access: yesSleep Research, EarlyView.
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang   +4 more
wiley   +1 more source

Quantitative Imaging of Water Diffusion in Brain Parenchyma at Cellular Resolution Using Stimulated Raman Scattering Microscopy

open access: yesSmall, EarlyView.
A multimodal multiphoton imaging framework enables high‐resolution quantification of water diffusion in brain tissue. By tracking deuterated water via stimulated Raman scattering (SRS) microscopy, this study resolves the microscopic heterogeneity of water diffusion at cellular resolution and determines apparent diffusion coefficients in health and ...
Wakana Ozaki   +4 more
wiley   +1 more source

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen   +9 more
wiley   +1 more source

Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

open access: yesNeural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source

Glymphatic system and Spaceflight Associated Neuro-Ocular Syndrome

open access: yes, 2022
A spectrum of ophthalmic abnormalities, including optic disc edema, globe flattening, chorioretinal folds, and hyperopic refractive error shifts, has been observed in astronauts during and after long-duration spaceflight.
Wostyn, Peter   +3 more
core   +1 more source

Association of enlarged perivascular space burden with silent cerebral infarcts in children with sickle cell disease

open access: yesBritish Journal of Haematology, EarlyView.
Enlarged perivascular spaces (ePVS) in the basal ganglia and centrum semiovale are highly prevalent in children with sickle cell disease (SCD). Enlarged PVS in the basal ganglia are associated with the presence of silent cerebral infarcts, another marker of neurological disease, in children with SCD. Summary Children with sickle cell disease (SCD) have
Kristine A. Karkoska   +6 more
wiley   +1 more source

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