Results 61 to 70 of about 24,909,638 (279)
Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases [PDF]
The lymphatic clearance pathways of the brain are different compared to the other organs of the body and have been the subject of heated debates. Drainage of brain extracellular fluids, particularly interstitial fluid (ISF) and cerebrospinal fluid (CSF),
Aldea, Roxana +7 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Impairment of the glymphatic system after diabetes [PDF]
Journal of Cerebral Blood Flow & Metabolism, 2016 The glymphatic system has recently been shown to clear brain extracellular solutes and abnormalities in glymphatic clearance system may contribute to both initiation and progression of neurological diseases. Despite that diabetes is known as a risk factor for vascular diseases, little is known how diabetes affects the glymphatic system.
Jiang, Quan +9 more
openaire +3 more sources
Impaired glymphatic transport in hypoxic-ischemic encephalopathy
NeuroImageHypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal brain injury. The glymphatic system aids in waste clearance via perivascular pathways and is crucial in maintaining brain functions.
Jieyi Shen +7 more
doaj +1 more source
JCI Insight, 2021 Status epilepticus (SE) is a neurological emergency usually accompanied by acute cerebral edema and long-term cognitive impairment, and is characterized by neurodegeneration and aberrant hyperphosphorylated tau protein (p-tau) aggregation.
Kewei Liu +9 more
doaj +1 more source
Can better management of periodontal disease delay the onset and progression of Alzheimer’s disease? [PDF]
A risk factor relationship exists between periodontal disease and Alzheimer’s disease (AD) via tooth loss, and improved memory following dental intervention.
Crean, Stjohn +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan +12 more
wiley +1 more source
Auditory Stimulation of Slow‐Wave Sleep Promotes Recovery after Brain Injury in an Animal Model
Annals of Neurology, EarlyView.Objective Traumatic brain injury (TBI) significantly reduces the quality of life for millions of survivors worldwide, causing persistent brain tissue damage and cognitive impairments, with no established therapeutic interventions currently available.
Carlos G. Moreira +9 more
wiley +1 more source
Journal of NanobiotechnologyThe glymphatic system plays an important role in the transportation of cerebrospinal fluid (CSF) and the clearance of metabolite waste in brain. However, current imaging modalities for studying the glymphatic system are limited.
Bin Sun +4 more
doaj +1 more source
Obstructive sleep apnea severity affects amyloid burden in cognitively normal elderly a longitudinal study [PDF]
Recent evidence suggests that Obstructive Sleep Apnea (OSA) may be a risk factor for developing Mild Cognitive Impairment and Alzheimer’s disease.
Bubu, Omonigho M. +3 more
core +1 more source