Results 81 to 90 of about 12,211 (230)

Evaluation of Soluble Triggering Receptor Expressed on Myeloid Cells 2 (sTREM2) in Cerebrospinal Fluid, Serum, and Plasma Using the Fully Automated Lumipulse Platform

Journal of Clinical Laboratory Analysis, EarlyView.
Relationship between serum and CSF sTREM2 concentration. ABSTRACT Background In this study, we first evaluated the relationship between sTREM2 concentrations in CSF, serum, and plasma of Alzheimer's disease (AD) patients using the newly developed Lumipulse G sTREM2 assay.
Luisa Agnello, Anna Maria Ciaccio, Fabio Del Ben, Caterina Maria Gambino, Tommaso Piccoli, Mauro Midiri, Concetta Scazzone, Anna Masucci, Martina Tamburello, Marcello Ciaccio   +9 more
wiley   +1 more source

Is sleep disruption a risk factor for Alzheimer’s disease? [PDF]

, 2017
Sleep disturbances are routinely encountered in Alzheimer’s disease (AD) and affect about 25–40% of patients in the mild-to-moderate stages of the disease. In many, sleep pathology may represent a symptom of the underlying neurodegeneration.
Aharon-Peretz, Ancoli-Israel, Ancoli-Israel, Ancoli-Israel, Ancoli-Israel, Anderson, Andreou, Anstey, Aston-Jones, Avidan, Baehr, Barnes, Bero, Bhatt, Binder, Bliwise, Brody, Brookmeyer, Brookmeyer, Bu, Buckner, Campbell, Chaudhury, Chemelli, Chen, Chen, Cirrito, Cooke, Dowling, Elwood, Emamian, Ferini-Strambi, Fisk, Gao, Gardner, Gonzalez, Haba-Rubio, Hahn, Hampp, Hara, Hardy, He, Hebert, Heinonen, Herring, Horovitz, Huang, Jack, Jagust, Jonghe, Jonsson, Ju, Ju, Kamenetz, Kang, Kosaka, Kosaka, Kuusisto, Latreille, Levy-Lahad, Le’na, Li, Lim, Lim, Lin, Lucey, Mander, Marien, McKinley, Mendelsohn, Merrilees, Mieda, Mochizuki, Moran, Nir, Nishi, Nishino, Ooms, Ooms, Osorio, Osorio, O’Donnell, Peters, Petit, Peyron, Potvin, Prince, Prinz, Qiu, Reid, Ren, Rey, Richter, Rogaev, Ruby, Sakurai, Saper, Schmechel, Sherrington, Someya, Sperling, Spira, Sprecher, Sterniczuk, Strittmatter, Sun, Sämann, Tranah, Troussière, van Someren, Wang, Webster, Xie, Yaffe, Yamakawa, Yu, Zhang, Zhang   +117 more
core   +1 more source

Emerging Issues for Counselors Applying Neuroscience With Black Clients: Avoiding Scientific Racism

Journal of Multicultural Counseling and Development, EarlyView.
ABSTRACT Neuroscience‐infused methods are heavily impacting the manner in which counselors, educators, and researchers approach working with clients and conducting research. While some scholars perceive neuroscience as scientifically objective and culturally neutral, that is not entirely true.
Isaac Burt
wiley   +1 more source

Glymphatic system and aquaporin‑4 in epilepsy

Acta Neurobiologiae Experimentalis, 2023
Over the past decade glymphatic concept has gained more and more interest. Despite some lacking data regarding structural and functional aspects, glymphatic system is widely considered the main mechanism of water and solutes transport in brain parenchyma, as well as waste clearance from the brain.
openaire   +2 more sources

T2‐Weighted T1 Mapping and Automated Segmentation of CSF: Assessment of Solute Gradients in the Healthy Brain

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Cerebrospinal fluid (CSF) serves as a medium for nutrient delivery and waste clearance. The T1 relaxation rate, R1, can be used to measure the concentration of intrinsic solutes and extrinsic contrast agents. Purpose To implement a method for R1 mapping and segmentation of CSF and to use this method to explore how R1 of CSF relates ...
Tryggve Holck Storås, Sofie Lysholm Lian, Ingrid Mossige, Jørgen Riseth, Siri Fløgstad Svensson, Grethe Løvland, Geir Ringstad, Kent‐André Mardal, Kyrre Eeg Emblem, Kaja Nordengen   +9 more
wiley   +1 more source

The role and mechanism of Aβ clearance dysfunction in the glymphatic system in Alzheimer’s disease comorbidity

Frontiers in Neurology
Alzheimer’s disease (AD) is the leading type of dementia globally, characterized by a complex pathogenesis that involves various comorbidities. An imbalance in the production and clearance of amyloid β-protein (Aβ) peptides in the brain is a key ...
Hailang Li, Qianqian Yao, Xueyan Huang, Xiaoyan Yang, Changyin Yu   +4 more
doaj   +1 more source

Simultaneous Assessment of Intracranial Artery and Paravascular CSF Pulsation Using 3D Whole‐Brain Diffusion‐Prepared Cine bSSFP (DECAF) MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose a noninvasive and quantitative MRI approach to simultaneously assessing intracranial artery pulsation and paravascular cerebrospinal fluid (CSF) pulsation in the human brain. Methods We developed a 3D whole‐brain Diffusion‐prepared Cine bSSFP (DECAF) MRI technique, with improved motion‐sensitized driven‐equilibrium providing
Chang Ni, Xiangjian Hou, SeyyedKazem HashemizadehKolowri, Seong‐Eun Kim, Qiuting Wen, Nicholas A. Frost, J. Scott McNally, Chun Yuan, Xiaodong Ma   +8 more
wiley   +1 more source

Cell-to-Cell Communication in Learning and Memory: From Neuro- and Glio-Transmission to Information Exchange Mediated by Extracellular Vesicles [PDF]

, 2019
Most aspects of nervous system development and function rely on the continuous crosstalk between neurons and the variegated universe of non-neuronal cells surrounding them.
Di Liegro, Carlo Maria, Di Liegro, Italia, Schiera, Gabriella   +2 more
core   +1 more source

Association between sleep duration and cognitive function and emotional disorders in middle‐aged and elderly patients with cerebral small vessel disease

Sleep Research, EarlyView.
Abstract Objectives To investigate the association between the sleep duration with cognitive impairment in middle‐aged and elderly patients with cerebral small vessel disease (CSVD). Methods This cross‐sectional study enrolled hospitalized patients aged ≥55 years diagnosed with CSVD between November 2021 and August 2023.
Chunmei Long, Yunying Wu, Sha Wang, Ziwei Gong, Ye Wang   +4 more
wiley   +1 more source

Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

Neural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source