Results 81 to 90 of about 17,183,881 (176)

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

Glymphatic System Pathology and Neuroinflammation as Two Risk Factors of Neurodegeneration

Cells
The key to the effective treatment of neurodegenerative disorders is a thorough understanding of their pathomechanism. Neurodegeneration and neuroinflammation are mutually propelling brain processes.
Stanisław Szlufik, Kamila Kopeć, Stanisław Szleszkowski, Dariusz Koziorowski   +3 more
doaj   +1 more source

Glymphatic System in Adolescents with Major Depressive Disorder: No Dysfunction and No Association with Poor Sleep Quality [PDF]

Jie Zhang,1 Xingxiong Zou,1 Xianjie Cai,2 Menghong Zou,1 Hongwei Li,1 Ruohan Feng1 1Department of Radiology, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang Sichuan, 621000, People’s Republic of China; 2Department of Radiology, MOE
Zou X, Li H, Zhang J, Zou M, Feng R, Cai X   +5 more
core  

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

British Journal of Clinical Pharmacology, EarlyView.
Jakša Vukojević, Luka Horvat, Vito Papić, Andrija Štajduhar   +3 more
wiley   +1 more source

Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)

Journal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.
India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw, Michael Cramberg, Matthew Dille, Emily Pick, Mary Thompson, Bruce A. Young   +5 more
wiley   +1 more source

Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén, Anna Lindam, Dan Farahmand, Anne‐Marie Landtblom, Katarina Laurell   +4 more
wiley   +1 more source

Phenotypic Variability in Slow‐Wave Sleep in Depression: Associations With Clinical Profiles and Disorder Severity

Journal of Sleep Research, EarlyView.
ABSTRACT Slow‐wave sleep (SWS; stage N3) is often reported as reduced in depression, yet variability across depressive phenotypes remains poorly characterised. This study aimed to determine whether N3 architecture—proportion, duration, and latency—identifies clinically distinct profiles in major depressive episode (MDE).
Antoine Salmeron, Pierre A. Geoffroy, Lily Vissouze, Jeanne Leseur, Heloise Rach, Michel Lejoyeux, Justine Frija, Marie Pia d’Ortho, Julia Maruani   +8 more
wiley   +1 more source

A new glaucoma hypothesis: a role of glymphatic system dysfunction [PDF]

, 2015
: In a recent review article titled A new look at cerebrospinal fluid circulation, Brinker et al. comprehensively described novel insights from molecular and cellular biology as well as neuroimaging research, which indicate that cerebrospinal fluid (CSF)
Hanspeter Esriel Killer, Veva De Groot, Wostyn, Peter, Killer, Hanspeter Esriel, Peter Wostyn, De Deyn, Peter Paul, Audenaert, Kurt, De Groot, Veva, Debby Van Dam, Van Dam, Debby, Kurt Audenaert, Peter Paul De Deyn   +11 more
core   +2 more sources

Sleep and the Glymphatic System - A Systematic Review

, 2021
This study aims to review and summarize the dynamic relationship between sleep and the glymphatic system. Specifically, we will examine the association between sleep and the glymphatic system in samples of typically developing individuals and those ...
Dea Garic, Pearlynne Li Hui Chong, A. J. Schwichtenberg, Mark Shen   +3 more
core   +1 more source

Interview with Ruotong Chen, recipient of the 2026 Epilepsia Open Prize for Clinical Research

Epilepsia Open, EarlyView.
Merab Kokaia, Piero Perucca
wiley   +1 more source