Results 101 to 110 of about 17,183,881 (176)

The Ocular Glymphatic System—Current Understanding and Future Perspectives

The ocular glymphatic system subserves the bidirectional polarized fluid transport in the optic nerve, whereby cerebrospinal fluid from the brain is directed along periarterial spaces towards the eye, and fluid from the retina is directed along ...
Christine Delle, Delle, Christine, Wang, Xiaowei, Maiken Nedergaard, Nedergaard, Maiken, Xiaowei Wang   +5 more
core   +1 more source

The glymphatic system and cerebral small vessel disease [PDF]

Objectives: Cerebral small vessel disease is a group of pathologies in which alterations of the brain's blood vessels contribute to stroke and neurocognitive changes.
Zhang, Douglas M., Azizi, Saara-Anne, Brorson, James R., Norton de Matos, Salvador A., Ang, Phillip S.   +4 more
core   +1 more source

Coupling between global brain blood oxygen level‐dependent activity and cerebrospinal fluid dynamics in young endurance athletes

Experimental Physiology, EarlyView.
Abstract Cerebrospinal fluid (CSF) contributes to brain waste clearance through its coupling with cerebral haemodynamics. Aerobic exercise promotes brain health, but its influence on brain waste clearance remains unclear. This study examined the coupling between CSF and cerebral haemodynamics in endurance athletes. Fifteen young male endurance athletes
Daisuke Hoshi, Marina Fukuie, Ryota Asahara, Tsubasa Tomoto, David C. Zhu, Rong Zhang, Keigo Ohyama‐Byun, Seiji Maeda, Jun Sugawara, Takashi Tarumi   +9 more
wiley   +1 more source

“Glymphatic” Neurodegeneration: Is Sleep the Missing Key?

Clinical and Translational Neuroscience
Robust evidence suggests that the glymphatic system plays a key role in preserving brain health. Indeed, its activity in maintaining homeostasis by clearing neurotoxic proteins such as beta-amyloid from the human brain is essential.
Luigi Ferini-Strambi, Maria Salsone
doaj   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Glymphatic system function in patients with ischemic stroke evaluated by the DTI-ALPS method: a comprehensive review

Frontiers in Neurology
The glymphatic system is a glial-dependent waste clearance pathway in the central nervous system (CNS) of vertebrates that exploits the perivascular compartment between the vascular basement membrane (outermost wall of blood vessels) and astrocytic ...
Lichuan Zeng, Lichuan Zeng, Lichuan Zeng, Zihan Yin, Wei Li, Xiao Wang, Yaodan Zhang, Mingguo Xie, Ling Zhao   +8 more
doaj   +1 more source

Cerebral blood flow in conscious rats and implications for therapeutic interventions

Experimental Physiology, EarlyView.
Abstract Cerebral blood flow (CBF) often becomes compromised in patients suffering from cardiovascular diseases, increasing the risk of neurodegenerative disease and vascular dementia. There is an urgent need for treatments to address cardiovascular risk without compromising brain perfusion, yet the impact of many existing treatments on CBF are not ...
Tonja W. Emans, Courtney R. Brighouse, Jack T. Sloan, Fiona D. McBryde   +3 more
wiley   +1 more source

The glymphatic system and multiple sclerosis: An evolving connection [PDF]

Multiple sclerosis (MS) is a complex autoimmune disorder that affects the central nervous system, resulting in demyelination and an array of neurological manifestations.
Alghanimy, Alaa, Work, Lorraine M., Holmes, William M.   +2 more
core   +1 more source

Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls

Experimental Physiology, EarlyView.
Abstract Exercise in the heat and elevated tissue temperature are associated with neuronal stress and changes in blood–brain barrier (BBB) function. More severe thermal insult may manifest as exertional heat illness (EHI) and complication by central nervous system (CNS) dysfunction may persist post‐EHI.
Tom W. Palin, Jo Corbett, Lisa J. Hill, David R. Woods, Alex A. M. Gould, Barney Wainwright, James A. Roberts, Chloe N. Thomas, Daniel Snape, Carol House, Omar Tayari, Richard J. Elsworthy, James L. Mitchell, Andrew J. Roberts, John P. O'Hara, Michael J. Stacey   +15 more
wiley   +1 more source

The glymphatic system in migraine and other headaches

The Journal of Headache and Pain
AbstractGlymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial fluid, encompassing penetrating and pial vessels and communicating with the subarachnoid space.
Maria Grazia Vittorini, Aysenur Sahin, Antonin Trojan, Sevil Yusifli, Tamta Alashvili, Gonçalo V. Bonifácio, Ketevan Paposhvili, Viktoria Tischler, Christian Lampl, Simona Sacco, on behalf of the School of Advanced Studies of the European Headache Federation (EHF-SAS)   +10 more
openaire   +4 more sources