Results 101 to 110 of about 12,211 (230)

Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer's disease [PDF]

open access: yes, 2017
The vascular contributions to neurodegeneration and neuroinflammation may be assessed by magnetic resonance imaging (MRI) and ultrasonography (US). This review summarises the methodology for these widely available, safe and relatively low cost tools and ...
Azevedo, E.   +5 more
core   +1 more source

The structure, functions and clinical significance of the glymphatic system [PDF]

open access: yesEurasian Journal of Veterinary Sciences, 2021
The glymphatic system is a newly discovered waste cleaning system. It provides active removal of metabolites and soluble proteins from the central nervous system (CNS).
Tansu Kuşat, Emrah Sur
doaj  

Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy. [PDF]

open access: yes, 2018
Malignant gliomas carry a dismal prognosis. Conventional treatment using chemo- and radiotherapy has limited efficacy with adverse events. Therapy with genetically engineered T-cells, such as chimeric antigen receptor (CAR) T-cells, may represent a ...
Almeida, Neil D   +4 more
core  

A method for measuring blood pressure and cardiorespiratory oscillations [PDF]

open access: yes, 2017
Studies with magnetoencephalography (MEG) are still quite rarely combined simultaneously with methods that can provide a metabolic dimension to MEG investigations.
Hinrichs, Hermann   +6 more
core   +1 more source

Neurosurgery and the glymphatic system

open access: yesActa Neurochirurgica
Abstract The discovery of the glymphatic system has fundamentally altered our comprehension of cerebrospinal fluid transport and the removal of waste from brain metabolism. In the past decade, since its initial characterization, research on the glymphatic system has surged exponentially.
openaire   +2 more sources

Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén   +4 more
wiley   +1 more source

Poroelastic Modelling of CSF circulation via the incorporation of experimentally derived microscale water transport properties [PDF]

open access: yes, 2017
We outline how multicompartmental poroelasticity is applied to the study of dementia. We utilize a 3D version of our poroelastic code to investigate the effects within parenchymal tissue.
Chou, D   +11 more
core  

Brain interference: Revisiting the role of IFNγ in the central nervous system [PDF]

open access: yes, 2017
Interferon gamma (IFN-gamma) is a pro-inflammatory cytokine, first described as a secreted molecule capable of interfering with viral replication. Since then, numerous other important actions in the context of the immune response to invading pathogens ...
Cerqueira, João José   +4 more
core   +1 more source

Overnight Dynamics of Ventricular Cerebrospinal Fluid Amyloid‐Beta, Lactate and Hypocretin in Patients With Hydrocephalus: A Pilot Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT This pilot observational study evaluated whether frequent overnight sampling of ventricular cerebrospinal fluid could clarify how sleep, hypocretin and lactate relate to amyloid‐β42 dynamics in adults with hydrocephalus. Seven participants underwent hourly ventricular cerebrospinal fluid sampling from early evening to late morning during ...
Casper Schwartz Riedel   +4 more
wiley   +1 more source

An Electroencephalographic Study of Sleep Spindle and Infraslow Oscillation in Children With Autism Spectrum Disorder

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT We investigated whether sleep microstructures show spatial differences in young children with autism compared with typically developing peers. 32‐channel electroencephalography (EEG) during natural sleep after 5–6 h of partial sleep deprivation was recorded from 53 children (26 with autism, 27 typically developing; 1.1–5.1 years).
Kevin Liu   +7 more
wiley   +1 more source

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