Results 61 to 70 of about 11,518 (273)

Investigating cerebral oedema using poroelasticity [PDF]

open access: yes, 2015
Cerebral oedema can be classified as the tangible swelling produced by expansion of the interstitial fluid volume. Hydrocephalus can be succinctly described as the abnormal accumulation of cerebrospinal fluid (CSF) within the brain which ultimately leads
Chou, D   +6 more
core   +1 more source

Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]

open access: yes, 2018
Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro   +8 more
core   +1 more source

The relationship between inflammation, impaired glymphatic system, and neurodegenerative disorders: A vicious cycle

open access: yesNeurobiology of Disease
The term “glymphatic” emerged roughly a decade ago, marking a pivotal point in neuroscience research. The glymphatic system, a glial-dependent perivascular network distributed throughout the brain, has since become a focal point of investigation.
Yu Cai   +7 more
doaj   +1 more source

Stress and the glymphatic system

open access: yes, 2020
Psychoneuroendocrinoimmunology (PNEI) is an integrative discipline studying the processes by which mental events modulate immune functions and how the immune system in turn can alter brain function. The central nervous system (CNS) is the only system in the body lacking its own anatomically defined lymphatic vessels.
Mariya Ivanovska   +2 more
openaire   +2 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

open access: yesAdvanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba   +20 more
wiley   +1 more source

Obstructive sleep apnea severity affects amyloid burden in cognitively normal elderly a longitudinal study [PDF]

open access: yes, 2018
Recent evidence suggests that Obstructive Sleep Apnea (OSA) may be a risk factor for developing Mild Cognitive Impairment and Alzheimer’s disease.
Bubu, Omonigho M.   +3 more
core   +2 more sources

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol   +3 more
wiley   +1 more source

Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism. [PDF]

open access: yes, 2016
A "glymphatic system," which involves convective fluid transport from para-arterial to paravenous cerebrospinal fluid through brain extracellular space (ECS), has been proposed to account for solute clearance in brain, and aquaporin-4 water channels in ...
Jin, Byung-Ju   +2 more
core  

Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery [PDF]

open access: yes, 2015
Despite the extensive media coverage associated with the diagnosis of chronic traumatic encephalopathy (CTE), our fundamental understanding of the disease pathophysiology remains in its infancy.
Anthony L. Petraglia   +9 more
core   +2 more sources

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