Results 161 to 170 of about 192,172 (285)

Pathogenic GM-CSF drives functional diversification of inflammatory macrophages in autoimmune arthritis. [PDF]

Sci Adv
Mukoyama H, Takeuchi Y, Ohara D, Lee Y, Watanabe H, Kato H, Kondoh G, Morinobu A, Hirota K.   +8 more
europepmc   +1 more source

Enhanced Sensitivity of a Modified Quaking‐Induced Conversion Diagnostic Test for the Broad Detection of Sporadic and Inherited Prion Diseases: A Retrospective Study

Annals of Neurology, EarlyView.
Objective Quaking‐induced conversion (QuIC) tests, which detect prion‐seeding activity in cerebrospinal fluid (CSF), have markedly advanced the antemortem diagnosis of prion diseases such as Creutzfeldt‐Jakob disease (CJD). These tests provide high diagnostic accuracy and enable timely differentiation from other rapidly progressive neurodegenerative ...
Jennifer Myskiw, Rebecca Fox, Dominic M.S. Kielich, Lise Lamoureux, Melanie Leonhardt, Olivia Nykvist, Jessy A. Slota, Kristen Avery, Clark Phillipson, Kathy Frost, Sharon Simon, Brian S. Appleby, Ben A. Bailey‐Elkin, Stephanie A. Booth   +13 more
wiley   +1 more source

Tofacitinib repairs inflammation and mitochondrial dysregulation in GM-CSF-reprogrammed RA macrophages. [PDF]

Cell Mol Immunol
Satoeya N, Zack SR, Zoubi OA, Umar S, Burgos A, Abdulrab S, Zanotti B, Volin MV, Karam JA, Xia Y, Umali DC, Arami S, Al-Awqati M, Chang HT, O'Neill LAJ, Schett G, Sweiss N, Shahrara S.   +17 more
europepmc   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

Lipid nanoparticle GM-CSF replacement for autoimmune pulmonary alveolar proteinosis. [PDF]

Proc Natl Acad Sci U S A
Lian L, Jang B, Huayamares SG, Shakked A, Gentry K, Zenhausern R, Radmand A, Schrader Echeverri E, Parihar VC, Guerrero-Ferreira RC, Calkins R, Vanover D, Santangelo PJ, Kim H, Dahlman JE.   +14 more
europepmc   +1 more source

GM-CSF Receptor [PDF]

, 2020
openaire   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Biosynthetic OMVs with endogenous GM-CSF loading for ultrasound-triggered in situ cancer vaccination. [PDF]

J Nanobiotechnology
Zhang R, Zhang B, Duan S, Xu X, Jiang R, Zhao Y, Li Z, Zhang X, Yang S, Sang M, Zhang L, Zhang J, Wang Y, Zhang L.   +13 more
europepmc   +1 more source

Linezolid‐mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition

Arthritis &Rheumatology, EarlyView.
Objective Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H. W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Oncolytic Virus VV-GMCSF-Lact and Human GM-CSF Against GL261 Glioma in Immunocompetent Mice. [PDF]

Pharmaceuticals (Basel)
Ageenko AB, Vasileva NS, Chesnokova AS, Semenov DV, Byvakina AA, Dymova MA, Sen'kova AV, Nushtaeva AA, Leonteva AA, Savinovskaya YI, Kochneva GV, Richter VA, Kuligina EV.   +12 more
europepmc   +1 more source