Results 151 to 160 of about 332,782 (345)

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

CD116 (GM-CSF-R)

open access: yes, 2001
Human CD116 is the alpha subunit of granulocytemacrophage colony stimulating factor receptor (GMCSFR, also called colony stimulating factor 2 receptor, alpha) that binds GM-CSF with low affinity.
Lanza F   +5 more
core  

Differential Expression of M-CSF, G-CSF, and GM-CSF by Human Monocytes

open access: yes, 1990
The colony-stimulating factors (CSF) belong to a group of proteins which regulate blood cell production. Human monocytes allowed to adhere express high levels of M-CSF transcripts and secreted protein at 24 h in the presence but not in the absence of ...
Kenneth Kaushansky   +3 more
core   +1 more source

Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations

open access: yesAngewandte Chemie, EarlyView.
Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera   +2 more
wiley   +2 more sources

Therapeutic properties of a vector carrying the HSV thymidine kinase and GM-CSF genes and delivered as a complex with a cationic copolymer [PDF]

open access: gold, 2015
И. В. Алексеенко   +17 more
openalex   +1 more source

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

open access: yesAnnals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi   +33 more
wiley   +1 more source

Enantioselective Synthesis of a New Class of Stable and Functionalized Cyclopentadienes via CuH‐Catalysis

open access: yesAngewandte Chemie, EarlyView.
Cyclopentadienes (CpHs) are fundamental building blocks with widespread applications in chemistry. However, their inherent acidity and isomeric instability have long limited access to chiral variants in an asymmetric fashion. Here, we introduce a CuH‐catalyzed asymmetric transformation that provides an unprecedented entry into a new class of ...
Piero Soppelsa   +4 more
wiley   +2 more sources

GM-CSF/IL-3/IL-5 receptor common β chain (CD131) expression as a biomarker of antigen-stimulated CD8+ T cells [PDF]

open access: gold, 2008
Silvia Selleri   +11 more
openalex   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

open access: yesAnnals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones   +54 more
wiley   +1 more source

Expanding High‐Fidelity Multiplexing in Ultrasensitive Single‐Molecule Protein Detection via Proximity Barcoding

open access: yesAngewandte Chemie, EarlyView.
We develop an ultrasensitive, high‐accuracy multiplex protein detection platform integrating high‐throughput single‐molecule protein detection with proximity ligation. Using paired DNA barcodes, this platform breaks the digital immunoassay multiplexing ceiling imposed by cross‐reactivity and fluorescence spectral overlap, providing a broadly accessible
Chi‐Chia Wang, Emily Dorsey, Connie Wu
wiley   +2 more sources

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