Elevated nitric oxide during colitis restrains GM-CSF production in ILC3 cells via suppressing an AhR-Cyp4f13-NF-κB axis. [PDF]
Zhao X +14 more
europepmc +1 more source
ABSTRACT Background Pathophysiological changes affect tissue cell composition and density. For example, neurodegenerative disorders and brain tumors are associated with cell loss and abnormal accumulation, respectively. In these scenarios, if monitored and tracked, tissue cellularity might be used to inform clinical diagnosis and management. Purpose To
Giulia Debiasi +7 more
wiley +1 more source
GM-CSF-mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to <i>Aspergillus fumigatus</i>. [PDF]
Mills KAM +14 more
europepmc +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
High-altitude hypoxia exacerbates chemotherapy-induced myelosuppression by lowering serum G-CSF/GM-CSF and regulating apoptosis and proliferation. [PDF]
Shi J +6 more
europepmc +1 more source
Abstract Objectives We aimed to summarise findings on blood cytokine levels in patients with paediatric‐onset inflammatory bowel disease (PIBD) compared to healthy controls. Methods This systematic review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines and was registered at Prospero (CRD42024579684 ...
Sabine Jansson +7 more
wiley +1 more source
Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice. [PDF]
Wang J, Kong D.
europepmc +1 more source
Predicting Different Recurrence Risk in HNSCC Using Circulating Inflammatory and T‐Cell Biomarkers
ABSTRACT Objective Head and neck squamous cell carcinoma (HNSCC) lacks reliable prognostic circulating biomarkers, and the role of the immune system in its progression remains incompletely understood. This study aimed to evaluate the prognostic value of systemic inflammatory and immune biomarkers in surgically treated patients with primary oral cavity (
Riccardo Gili +10 more
wiley +1 more source
Reduced plasma levels of GM-CSF is a common feature of <i>Schistosoma mansoni</i>-infected school-aged children. [PDF]
Kamdem SD +8 more
europepmc +1 more source
Decreased PD-L1 contributes to preeclampsia by suppressing GM-CSF via the JAK2/STAT5 signal pathway. [PDF]
Tian Y, Peng X, Yang X.
europepmc +1 more source

