Results 41 to 50 of about 332,782 (345)

GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function

Frontiers in Immunology, 2018
GM-CSF promotes myeloid differentiation of cultured bone marrow cells into cells of the granulocytic and monocytic lineage; the latter can further differentiate into monocytes/macrophages and dendritic cells.
Li Sun, Jai Rautela, Jai Rautela, Rebecca B. Delconte, Rebecca B. Delconte, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes, Emma M. Carrington, Emma M. Carrington, Robyn L. Schenk, Robyn L. Schenk, Marco J. Herold, Marco J. Herold, Nicholas D. Huntington, Nicholas D. Huntington, Andrew M. Lew, Andrew M. Lew, Andrew M. Lew, Yuekang Xu, Yifan Zhan, Yifan Zhan, Yifan Zhan   +21 more
doaj   +1 more source

GM-CSF-primed human neutrophils produce a robust intracellular respiratory burst when stimulated with viable STm.

, 2018
(A) PMNs in NHS were either unprimed or primed with GM-CSF +/- IL-8 and stimulated with STm (MOI 50:1).
Helene L. Andrews-Polymenis (132780), Johanna R. Elfenbein (795278), Trina L. Westerman (5738243), Lydia Bogomolnaya (356945), M. Katherine Sheats (5738246)   +4 more
core   +1 more source

Functional Granulocyte–Macrophage Colony-Stimulating Factor (GM-CSF) Delivered by Canine Histiocytic Sarcoma Cells Persistently Infected with Engineered Attenuated Canine Distemper Virus

Pathogens, 2023
The immune response plays a key role in the treatment of malignant tumors. One important molecule promoting humoral and cellular immunity is granulocyte–macrophage colony-stimulating factor (GM-CSF). Numerous successful trials have led to the approval of
Katarzyna Marek, Federico Armando, Thanaporn Asawapattanakul, Vanessa Maria Nippold, Philippe Plattet, Gisa Gerold, Wolfgang Baumgärtner, Christina Puff   +7 more
doaj   +1 more source

GM-CSF & Implantation

, 2023
Βιβλιογραφία: σ. 36-47Η εμφύτευση του εμβρύου είναι μια διαδικασία πολλαπλών σταδίων, η ρύθμιση της οποίας εξαρτάται από διαμοριακές και ενδοκυτταρικές αλληλεπιδράσεις και η επιτυχία της εξαρτάται σε μεγάλο βαθμό από μια αμφίδρομη σηματοδότηση μεταξύ του
'Ήλιου, Τριανταφυλιά, Iliou, Triantafylia   +1 more
core   +1 more source

GM-CSF production by immune cells in steady state and autoimmune neuroinflammation mapped using fate reporting mice. [PDF]

Front Immunol
IntroductionGM-CSF is a pro-inflammatory cytokine that promotes an inflammatory phenotype in myeloid cells. The extent and pattern of GM-CSF expression in immune cells have not been fully elucidated.
Azizi G, Rasouli J, Naziri H, Gonzalez MV, Garifallou J, Zhang GX, Ciric B, Rostami A.   +7 more
europepmc   +2 more sources

Malaria Pigment Hemozoin Impairs GM-CSF Receptor Expression and Function by 4-Hydroxynonenal

Antioxidants, 2021
Malarial pigment hemozoin (HZ) generates the lipoperoxidation product 4-hydroxynonenal (4-HNE), which is known to cause dysregulation of the immune response in malaria. The inhibition of granulocyte macrophage colony-stimulating factor (GM-CSF)-dependent
Oleksii Skorokhod, Valentina Barrera, Giorgia Mandili, Federica Costanza, Elena Valente, Daniela Ulliers, Evelin Schwarzer   +6 more
doaj   +1 more source

Pomalidomide counters GM-CSF-triggered CD14 and TLR downregulation and partly reverts the GM-CSF-induced effects on cytokine production.

, 2016
(a-d) Treatment with pomalidomide alone did not change monocyte TLR and CD 14 but revert the GM-CSF-induced downregulation of TLR1 (a), TLR2 (b), TLR4 (c) and CD14 (d).
Lukas Wisgrill (624486), Isabelle Wessely (3190410), Simone Schüller (3190404), Celia Dürr (3190401), Arnold Pollak (331546), Kambis Sadeghi (3190407), Andreas Spittler (117544), Elisabeth Förster-Waldl (359199), Armando Heinle (3190413), Susanne C. Diesner (359191), Monika Sachet (262810)   +10 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Blood stem cell collections after mobilization with combination chemotherapy containing ifosfamide followed by G-CSF in multiple myeloma [PDF]

, 2003
High-dose chemotherapy with autologous peripheral blood stem cell transplantation is the standard treatment of patients with multiple myeloma today. In this study we used a combination mobilizing chemotherapy containing ifosfamide with G-CSF before stem ...
Werding, N., Straka, C., Adler-Reichel, S., Emmerich, B., Einsele, H., Hebart, H.   +5 more
core   +1 more source