Advanced In vitro Human Immune Profiling of GMMA-based vaccines
Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles derived from engineered Gram-negative bacteria. GMMA, resembling bacteria outer membrane surface, provide a flexible platform for the vaccine development and GMMA-based ...
Tozzi Stefano +12 more
core +6 more sources
In vitro Human Immune Profiling to dissect the immunological response induced by GMMA candidate vaccines [PDF]
, 2023 Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles purified from Gram-negative bacteria genetically mutated to increase blebbing and reduce risk of reactogenicity, through modification of the lipid A portion of ...
Tondi, Serena
core +4 more sources
Vaccines, 2021 Salmonella Typhimurium (STm) represents the most prevalent cause of invasive non-typhoidal Salmonella (iNTS) disease, and currently no licensed vaccine is available.
Fabio Fiorino +6 more
doaj +2 more sources
Oficjum Ave Gmma Claritatis w źródłach XIII-XVI wieku
Saeculum ChristianumAutor analizuje oficjum Ave gemma claritatis o św. Katarzynie Aleksandryjskiej. Występuje ono w niewielu źródłach, głównie z terenu Francji i centralnej Europy (Polska, Węgry). Autor wydzielił sześć zasadniczych grup manuskryptów i starodruków, w których
Czesław Grajewski
semanticscholar +3 more sources
GMMA as a ‘plug and play’ technology to tackle infectious disease to improve global health: context and perspectives for the future [PDF]
Expert Review of Vaccines, 2021 Introduction Generalized-Modules-for-Membrane-Antigens (GMMA) is a technology platform developed to design outer membrane vesicle (OMV)-based vaccines.
Diego Piccioli, E. Bartolini, F. Micoli
semanticscholar +3 more sources
MODULATION OF REACTOGENICITY OF GENERALIZED MODULES FOR MEMBRANE ANTIGENS (GMMA)BY GENETIC LIPID A MODIFICATION [PDF]
, 2014 Outer membrane particles from Gram-negative bacteria are attractive vaccine candidates as they present surface antigens in their natural environment and orientation.
Rossi, Omar
core +3 more sources
The iNTS-GMMA vaccine: a promising step in non-typhoidal Salmonella vaccine development
Expert Review of Vaccines, 2023 Peter D Skidmore, R. Canals, M. Ramasamy
semanticscholar +4 more sources
Advanced In vitro Immune Profiling of GMMA-based vaccines
Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles derived from engineered Gram-negative bacteria. GMMA, resembling bacteria outer membrane surface, provide a flexible platform for vaccine development.
Francesca Schiavetti +12 more
core +2 more sources
A GMMA-CPS-Based Vaccine for Non-Typhoidal Salmonella [PDF]
Vaccines, 2021 Non-typhoidal Salmonella are a major cause of gastroenteritis worldwide, as well as causing bloodstream infections in sub-Saharan Africa with a high fatality rate. No vaccine is currently available for human use. Current vaccine development strategies are focused on capsular polysaccharides (CPS) present on the surface of non-typhoidal Salmonella. This
Akosiererem S. Sokaribo +11 more
openaire +3 more sources
Immune responses to prototype GMMA vaccine against Neisseria meningitidis in Africa [PDF]
, 2015 \(Neisseria\) \(meningitides\) is a major cause of meningitis epidemics in sub-Saharan Africa. A promising broadly-protective vaccine approach is outer membrane particle-based vaccine comprising GMMA (Generalised Modules for Membrane Antigens). To better
Ispasanie, Emma Helena Berta
core +6 more sources