Results 231 to 240 of about 188,404 (288)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Sperm Sexing in Selected Animals and Humans: Methods, Applications, and Future Prospects

open access: yesAndrology, EarlyView.
ABSTRACT Background Sperm sexing is a technique that enables the selection of offspring sex by sorting spermatozoa based on their sex chromosomes. This technology has gained increasing attention due to its potential applications in both animal breeding and human‐assisted reproduction.
Domrazek Kinga, Jurka Piotr
wiley   +1 more source

ComFB, a widespread family of c-di-NMP receptor proteins. [PDF]

open access: yesProc Natl Acad Sci U S A
Samir S   +10 more
europepmc   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

Nationwide Implementation of Double Reflex Testing for Hepatitis Delta in Spain: Results From the Retrospective Phase of the Spain‐DDR Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola   +95 more
wiley   +1 more source

L-Type Ca<sub>v</sub>1.3 and HCN Channels Mediate Heart Rate Acceleration by Catecholamines. [PDF]

open access: yesCirc Res
Torre E   +18 more
europepmc   +1 more source

Combined therapy with dutasteride and tadalafil vs dutasteride or tadalafil monotherapy in benign prostatic hyperplasia: a randomised phase III trial

open access: yesBJU International, EarlyView.
Objectives To evaluate the efficacy and safety of a fixed‐dose combination (FDC) of dutasteride and tadalafil vs monotherapy in patients with benign prostatic hyperplasia (BPH). Patients and Methods This phase III trial enrolled 667 patients. After screening and washout, eligible patients were stratified by the baseline International Prostate Symptom ...
Seung Wook Lee   +20 more
wiley   +1 more source

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