Results 111 to 120 of about 3,060 (210)

Review of the Literature on Current Changes in the Timing of Pubertal Development and the Incomplete Forms of Early Puberty

open access: yesFrontiers in Pediatrics, 2019
Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys.
Giovanni Farello   +4 more
doaj   +1 more source

Effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection treatment cycle: A single‐center retrospective cohort study

open access: yesAndrology, Volume 13, Issue 7, Page 1757-1771, October 2025.
Abstract Background Current advances in high‐throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations in assisted reproductive techniques remain unclear.
Linlin Li   +4 more
wiley   +1 more source

Puberty and type 1 diabetes

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Various data on type 1 diabetes mellitus (T1DM) have showed that the incidence of T1DM peaks at puberty. However, diabetes control and complications could be adversely affected by the physiological changes of puberty.
Subhankar Chowdhury
doaj   +1 more source

Brain‐Derived Neurotrophic Factor (BDNF) and Sex Differences in Metabolic Regulation

open access: yesJournal of Neurochemistry, Volume 169, Issue 10, October 2025.
Brain‐derived neurotrophic factor (BDNF) is expressed in the hypothalamus of both female and male mice (left‐hand side of the panel); however, it exerts distinct functions in either sex, explaining some sexually dimorphic phenotypes in mice and humans (right‐hand side of the panel).
Ariane M. Zanesco, Licio A. Velloso
wiley   +1 more source

A review on role of medicinal plants in polycystic ovarian syndrome: Pathophysiology, neuroendocrine signaling, therapeutic status and future prospects [PDF]

open access: yes, 2018
Polycystic ovary syndrome (PCOS) is one of the most important gynecological disorders among reproductive-age women. In patients with PCOS, the secretion rate and metabolism of androgens and estrogens are disrupted.
Abasian, Z   +4 more
core  

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

open access: yesAdvanced Therapeutics, Volume 8, Issue 9, September 2025.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen   +2 more
wiley   +1 more source

Central Precocious Puberty: Update on Diagnosis and Treatment [PDF]

open access: yes, 2015
Central precocious puberty (CPP) is characterized by the same biochemical and physical features as normally timed puberty but occurs at an abnormally early age. Most cases of CPP are seen in girls, in whom it is usually idiopathic.
Chen, Melinda, Eugster, Erica A.
core   +1 more source

Genome‐wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures

open access: yesAlzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION Identifying pleiotropy for blood pressure (BP) and cognitive performance measures may indicate mechanistic links between hypertension and Alzheimer's disease (AD). METHODS We performed a pleiotropy genome‐wide association study (GWAS) for paired measures of systolic, diastolic, pulse, and mean arterial pressure with memory ...
Moonil Kang   +26 more
wiley   +1 more source

Polycystic ovary syndrome and impact on health

open access: yesMiddle East Fertility Society Journal, 2011
Polycystic ovary syndrome (PCOS) is a multifactorial, heterogeneous, complex genetic, endocrine and metabolic disorder, diagnostically characterized by chronic anovulation, polycystic ovaries and biochemical and clinical manifestations of ...
Gautam N. Allahbadia, Rubina Merchant
doaj   +1 more source

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