, 2013 Improvement to the immunogenicity of DNA vaccines was evaluated in a Mycobacterium tuberculosis (MTB) infection mouse model examining the combined effects of nonlytic Fc-fused IL-7 DNA (IL-7-nFc) and Flt3-ligand fused Mtb32 (F-Mtb32) DNA.
조상래
core +1 more source
Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials. [PDF]
, 2010 BACKGROUND: Phase III trials of the malaria vaccine, RTS, S, are now underway across multiple sites of varying transmission intensity in Africa. Heterogeneity in exposure, vaccine response and waning of efficacy may bias estimates of vaccine efficacy ...
Michael T White +11 more
core +1 more source
Timing feedback-inhibition of the male reproductive hormone axis [PDF]
, 2008 Hormonal methods of male contraception have addressed feedback-inhbition of the cascade of hormones that has evolved to regulate sperm production but high concentrations of testosterone (T) in the blood have not worked satisfactorily.
Gopal Gupta +4 more
core +1 more source
Reproductive parameters of lambs immunocastrated with anti-GnRH vaccine. [PDF]
Anim Reprod, 2021 Rocha LF +8 more
europepmc +1 more source
Contraceptive Effect of a Recombinant GnRH Vaccine in Adult Female Pigs [PDF]
, 2006 GonaCon™ is a gonadotropin releasing hormone (GnRH) contraceptive vaccine developed at the USDA National Wildlife Research Center (NWRC) that contains keyhole limpet hemocyanin (KLH) coupled to GnRH.
Miller, Lowell A. +2 more
core +1 more source
Behavioral Assessment Reveals GnRH Immunocastration as a Better Alternative to Surgical Castration
AnimalsCastration is often employed in animal management for reproductive control. However, it is important to evaluate its impact on animal welfare. In this study, we developed rat models for both surgical (n = 6) and GnRH immunocastration (n = 6) to assess ...
Liuxia Lin +8 more
doaj +1 more source
Immunocastration reduces aggressive and sexual behaviour in male pigs
Animal, 2010 The aim of this study was to evaluate the effectiveness of a gonadotropin-releasing hormone (GnRH) vaccine, Improvac™ (Pfizer Ltd), in suppressing aggressive and sexual behaviour of male pigs.
L. Rydhmer, K. Lundström, K. Andersson
doaj +1 more source
Immunocontraception of male and female giraffes using the GnRH vaccine Improvac®. [PDF]
Zoo Biol, 2022 Schwarzenberger F +13 more
europepmc +1 more source
Enhancing enterovirus A71 vaccine production yield by microcarrier profusion bioreactor culture
, 2017 [[abstract]]Hand, foot and mouth diseases (HFMD) are mainly caused by Enterovirus A71 (EV-A71) infections. Clinical trials in Asia conducted with formalin-inactivated EV-A71 vaccine candidates produced from serum-free Vero cell culture using either ...
Liu, CC;Wu, SC;Wu, SR;Lin, HY;Guo, MS;Hu, AYC;Chow, YH;Chiang, JR;Shieh, DB;Chong, P
core +1 more source
EVALUATION OF GNRH CONTRACEPTIVE VACCINE USING DOMESTIC SWINE AS A MODEL FOR FERAL HOGS [PDF]
, 2003 We determined the effect of a GnRH vaccine on reproductive function of sexually mature 5-month female and male domestic swine. The vaccine, GonaConTM, developed at NWRC contains a GnRH peptide conjugated to KLH, combined with AdjuVacTM adjuvant also ...
Rhyan, Jack +2 more
core +2 more sources