Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo +6 more
wiley +1 more source
Reflection Rumination Reduces Negative Emotional Processing During Goal-Directed Behavior: An ERP Study. [PDF]
Owens M, Renaud J, Healy AS.
europepmc +1 more source
An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese +10 more
wiley +1 more source
Suicide Prevention Measures at High-Risk Locations: A Goal-Directed Motivation Perspective. [PDF]
Joyner L +8 more
europepmc +1 more source
Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro +8 more
wiley +1 more source
Defining Goal-Directed Training for Children with Cerebral Palsy: A Scoping Review and Framework for Implementation. [PDF]
Shierk A +8 more
europepmc +1 more source
Uptake of Goal-Directed Therapies in a Multidisciplinary and Interdisciplinary Cardiology-Renal-Endocrine Clinic: A Research Letter. [PDF]
Ouimet JP +5 more
europepmc +1 more source
Elevated oxygen extraction during heart transplantation is associated with increased morbidity and mortality: Implications for goal-directed perfusion. [PDF]
Petrovic M +27 more
europepmc +1 more source
Separable cognitive and motor decline tracked across adult life-span for goal-directed navigation. [PDF]
Lancia GL +5 more
europepmc +1 more source
Intraoperative hypotension during robotic-assisted radical prostatectomy: A randomised controlled trial comparing standard goal-directed fluid therapy with hypotension prediction index-guided goal-directed fluid therapy. [PDF]
Cotoia A +7 more
europepmc +1 more source

