Results 51 to 60 of about 425,428 (324)
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Goal directed behavior and dyslexia [PDF]
Abstract Goal directed behavior is explained by two approaches: the first, which can be named as cybertetic (behavior is wieved as homeostatic and reflexive), and second, as cognitive approach, a learned response, (skills developed by whaching the behavior of another individual).
openaire +3 more sources
Goal Directed Conflict Resolution and Policy Refinement [PDF]
Peer ...
Aphale, Mukta Sumeet+2 more
core
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Frontoparietal representations of task context support the flexible control of goal-directed cognition. [PDF]
Cognitive control allows stimulus-response processing to be aligned with internal goals and is thus central to intelligent, purposeful behavior. Control is thought to depend in part on the active representation of task information in prefrontal cortex ...
Gordon, AM+4 more
core +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
Goal-directed self-talk used to self-regulate in male basketball competitions [PDF]
This study examined how goal-directed self-talk may help basketball players to self-regulate in stereotypical competitive situations: seconds before a challenging game, while clearly winning or clearly losing, and at the close of a tight game ...
Comoutos, N+4 more
core +1 more source
Increased Goal Tracking in Adolescent Rats Is Goal-Directed and Not Habit-Like
When a cue is paired with reward in a different location, some animals will approach the site of reward during the cue, a behavior called goal tracking, while other animals will approach and interact with the cue itself: a behavior called sign tracking ...
Analise N. Rode+2 more
doaj +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Semantic Robot Programming for Goal-Directed Manipulation in Cluttered Scenes
We present the Semantic Robot Programming (SRP) paradigm as a convergence of robot programming by demonstration and semantic mapping. In SRP, a user can directly program a robot manipulator by demonstrating a snapshot of their intended goal scene in ...
Jenkins, Odest Chadwicke+3 more
core +1 more source