Results 61 to 70 of about 200,215 (293)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Goal-directed fluid optimization based on stroke volume variation and cardiac index during one-lung ventilation in patients undergoing thoracoscopy lobectomy operations: a pilot study

Clinics, 2013
OBJECTIVES: This pilot study was designed to utilize stroke volume variation and cardiac index to ensure fluid optimization during one-lung ventilation in patients undergoing thoracoscopic lobectomies.
Jian Zhang, Chao Qin Chen, Xiu Zhen Lei, Zhi Ying Feng, Sheng Mei Zhu   +4 more
doaj   +1 more source

Goal-directed fluid therapy optimizes hemodynamics on the elderly patients undergoing lumbar decompressive surgery and reduces postoperative complications [PDF]

Jichu yixue yu linchuang, 2021
Objective To explore the impact of goal-directed fluid therapy(GDT) management strategy on the perioperative complications of elderly patients undergoing lumbar spine surgery.
XIA Di, XU Li, LI Xu, HUANG Yu-guang
doaj  

Intra-Operative Fluid Management in Adult Neurosurgical Patients Undergoing Intracranial Tumour Surgery: Randomised Control Trial Comparing Pulse Pressure Variance (PPV) and Central Venous Pressure (CVP) [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Fluid management in neurosurgery presents specific challenges to the anaesthesiologist. Dynamic parameters like Pulse Pressure Variation (PPV) have been used successfully to guide fluid management.
Shalini Cynthia Sundaram, Serina Ruth Salins, Amar Nandha Kumar, Grace Korula   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

New progress of goal-directed fluid therapy in enhanced recovery after surgery [PDF]

Jichu yixue yu linchuang, 2020
Goal-directed fluid therapy(GDFT) is an important method to accelerate patients rehabilitation after surgical operation. It can maintain the stability of hemodynamic indexes, balance of oxygen supply and demand, reduce the perioperative inflammatory ...
HE Xiao-yi, ZOU Xue-jun, XING Hao-ran
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Occupational therapy assessment of open-road driving performance: validity of directed and self-directed navigational instructional components

, 2004
OBJECTIVE: The purpose of this study was to validate an assessment tool used by occupational therapists to evaluate on-road driving performance. METHODS: The driving assessment was conducted over a 15-km route that consisted of a range of traffic ...
Wood, Joanne M., Joanne M. Wood, Kerry Mallon, Mallon, Kerry L.   +3 more
core   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source