Results 61 to 70 of about 492,815 (298)
Clinics, 2013 OBJECTIVES: This pilot study was designed to utilize stroke volume variation and cardiac index to ensure fluid optimization during one-lung ventilation in patients undergoing thoracoscopic lobectomies.
Jian Zhang +4 more
doaj +1 more source
Maladaptive behavior and affect regulation: A functionalist perspective. [PDF]
, 2020 Clinical science has benefited tremendously from taking seriously the proposition that putatively maladaptive behaviors serve psychological functions, prominently among these affect regulation (AR).
Johnson, Sheri L +4 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Goal-directed fluid therapy optimizes hemodynamics on the elderly patients undergoing lumbar decompressive surgery and reduces postoperative complications [PDF]
Jichu yixue yu linchuang, 2021 Objective To explore the impact of goal-directed fluid therapy(GDT) management strategy on the perioperative complications of elderly patients undergoing lumbar spine surgery.
XIA Di, XU Li, LI Xu, HUANG Yu-guang
doaj
First-line therapy in HER2 positive metastatic breast cancer. Is the mosaic fully completed or are we missing additional pieces? [PDF]
, 2016 The discovery of human epidermal growth factor receptor 2 (HER2) and its role in the biology of breast cancer and the subsequent development of HER2-targeted therapies, have dramatically improved clinical outcomes for women with early-stage and advanced ...
Cognetti F. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
New progress of goal-directed fluid therapy in enhanced recovery after surgery [PDF]
Jichu yixue yu linchuang, 2020 Goal-directed fluid therapy(GDFT) is an important method to accelerate patients rehabilitation after surgical operation. It can maintain the stability of hemodynamic indexes, balance of oxygen supply and demand, reduce the perioperative inflammatory ...
HE Xiao-yi, ZOU Xue-jun, XING Hao-ran
doaj
Reducing gastrointestinal anastomotic leak rates: Review of challenges and solutions [PDF]
, 2016 Various techniques and interventions have been developed in an effort to obviate gastrointestinal anastomotic leaks. This review is intended to delineate potential modifications that can be made to reduce the risk of anastomotic leaks following ...
Philllips, Benjamin
core +4 more sources
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source